108505002: Tramadol hydrochloride (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with glutamate receptor antagonist mechanism of action (substance)\NMDA receptor antagonist\Tramadol hydrochloride
\Substance categorized by disposition\Receptor agonist\Opioid receptor agonist\Tramadol hydrochloride

\Drug or medicament (substance)\Opioid receptor agonist\Tramadol hydrochloride
\Drug or medicament (substance)\Analgesic (substance)\Tramadol hydrochloride
\Drug or medicament (substance)\Central nervous system agent (substance)\Psychoactive substance\Central depressant\Tramadol hydrochloride

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Substance with ether structure (substance)\Tramadol hydrochloride

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tramadol hydrochloride	Is a	Tramadol-containing product	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Non-opioid analgesics	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Tramadol (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Has disposition	N-methyl-D-aspartate receptor antagonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Has disposition	Opioid receptor agonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	NMDA receptor antagonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is modification of (attribute)	Tramadol (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Opioid receptor agonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Analgesic (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Drug pseudoallergen by function	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Central depressant	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	éther	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	Substance with ether structure (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tramadol hydrochloride 100mg/2mL injection (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 100mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 150mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 200mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50mg soluble tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50mg m/r capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 100mg m/r capsule (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 150mg m/r capsule (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 200mg m/r capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50mg/sachet powder (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 100 mg effervescent powder for oral solution sachet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 75mg m/r tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 300mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 400mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Acetaminophen + tramadol hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing tramadol hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release orodispersible tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 300mg m/r capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg oral tablet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 400 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 400 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100 mg prolonged-release oral tablet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 150 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 150 mg prolonged-release oral tablet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100 mg prolonged-release oral capsule	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100 mg prolonged-release oral capsule	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 300 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 300 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 150 mg prolonged-release oral capsule	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 150 mg prolonged-release oral capsule	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg prolonged-release oral capsule	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg prolonged-release oral capsule	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 200 mg prolonged-release oral tablet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 200 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 200 mg prolonged-release oral capsule	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 200 mg prolonged-release oral capsule	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 75 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 75 mg prolonged-release oral tablet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg oral tablet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50mg/sachet powder (substance)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50mg/sachet powder (substance)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100 mg effervescent powder for oral solution sachet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100 mg effervescent powder for oral solution sachet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 100 milligram/2 milliliter conventional release solution for injection ampule	Has precise active ingredient	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 100 milligram/2 milliliter conventional release solution for injection ampule	Has basis of strength substance (attribute)	False	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 1 milligram/1 milliliter conventional release oral solution (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 1 milligram/1 milliliter conventional release oral solution (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 100 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 100 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tramadol hydrochloride 50 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg effervescent oral tablet	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 50 mg effervescent oral tablet	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely dexketoprofen 25 milligram and tramadol hydrochloride 75 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely dexketoprofen 25 milligram and tramadol hydrochloride 75 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol hydrochloride	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
173039019	Tramadol hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
601510018	Tramadol hydrochloride (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
173039019	Tramadol hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
173039019	Tramadol hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
601510018	Tramadol hydrochloride (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
601510018	Tramadol hydrochloride (substance)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
601510018	Tramadol hydrochloride (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
27261000188110	tramadol chlorhydrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846981000172114	chlorhydrate de tramadol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
27261000188110	tramadol chlorhydrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846981000172114	chlorhydrate de tramadol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module