126172005: Estradiol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Sex hormone\Substance with estrogen receptor agonist mechanism of action (substance)\Estradiol
\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Steroid hormone\Estradiol
\Substance categorized by disposition\Receptor agonist\Substance with estrogen receptor agonist mechanism of action (substance)\Estradiol

\Drug or medicament (substance)\Hormone\...

\Sex hormone\Substance with estrogen receptor agonist mechanism of action (substance)\Estradiol

\Steroid hormone\Estradiol

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Polycyclic compound\Steroid (substance)\...

\Estrane\Estradiol and/or estradiol derivative\Estradiol

\Steroid hormone\Estradiol

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Estradiol	Is a	Estrane	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Is a	Estradiol and/or estradiol derivative	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Is a	estrogeno	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Has disposition	Estrogen	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Has disposition	Gonadal hormone	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Is a	Substance with estrogen receptor agonist mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Has disposition	Estrogen receptor agonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol	Is a	Steroid hormone	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely ethinylestradiol 35 microgram and norethisterone 1 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 50 microgram and norethisterone 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl oestradiol + norethindrone acetate 20mcg/1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol + norethindrone acetate 30mcg/1.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 30 microgram and norgestrel 300 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol + norgestrel 0.05mg/0.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Fluid sample oestradiol level	Component	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Oestradiol 50micrograms/24hours vaginal ring	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing estrone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Norethisterone 170micrograms/24hours / Estradiol 50micrograms/24hours patche	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Norethisterone 250micrograms/24hours / Estradiol 50micrograms/24hours patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 35 microgram and norethisterone 750 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely estradiol valerate 2 milligram and medroxyprogesterone 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 4 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol+desogestrel 20micrograms/150micrograms tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Desogestrel 150 microgram and ethinylestradiol 30 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 30 microgram and levonorgestrel 150 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol+levonorgestrel 30micrograms/250micrograms tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 50 microgram and levonorgestrel 250 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 35 microgram and norethisterone 500 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol+norethisterone 35micrograms/1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 20 microgram and norethisterone acetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 30 microgram and norethisterone acetate 1.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol+gestodene 30micrograms/75micrograms tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol+gestodene+placebo 30micrograms/75micrograms tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 20 microgram and gestodene 75 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 35 microgram and norgestimate 250 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 20mcg+progestogen (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 30mcg+progestogen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 35mcg+progestogen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 50mcg+progestogen (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol + levonorgestrel 0.15mg/0.03mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estrasorb	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol topical emulsion	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol topical emulsion 0.05mg/day	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estrasorb topical emulsion 0.05mg/day	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Levonorgestrel 0.015mg/day + estradiol 0.045mg/day transdermal system	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Climara pro	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Levonorgestrel + estradiol transdermal system	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Climara pro levonorgestrel 0.015mg/day + estradiol 0.045mg/day transdermal system	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely estradiol 2.083 microgram/1 hour prolonged-release vaginal ring (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol 600micrograms / norelgestromin 6mg transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol- and norelgestromin-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Desogestrel + ethinyl estradiol + ethinyl oestradiol 0.15mg/0.01mg/0.01mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Desogestrel + ethinyl oestradiol 0.15mg/0.03mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 35 microgram and etynodiol diacetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl oestradiol + ethynodiol diacetate 50mcg/1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol + etonogestrel 2.7mg/11.7mg vaginal ring	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol + ferrous fumarate + norgestrel 0.03mg/75mg/0.3mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Norelgestromin+ethinyl estradiol 6mg/0.75mg patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 1.25g/dose gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol + norethisterone acetate 1mg/0.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely desogestrel 100 microgram and ethinylestradiol 25 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 0.75mg/dose gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely ethinylestradiol 5 microgram and norethisterone acetate 1 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 4.167 microgram/hour prolonged-release vaginal ring	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 20 microgram and ferrous fumarate 75 mg and norethisterone 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely ethinylestradiol 30 microgram and ferrous fumarate 75 milligram and norethisterone 1.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 35 microgram and norgestimate 180 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing ethinylestradiol and norgestimate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing ethinylestradiol and norethisterone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing desogestrel and ethinylestradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing ethinyl estradiol and ethynodiol diacetate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing ethinylestradiol and levonorgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Norethindrone + ethinyl oestradiol + ferrous fumarte	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol + norgestimate 0.035mg/0.25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol acetate (substance)	Is a	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 14mcg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing estradiol and norethisterone acetate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 0.05mg/norethindrone acetate 0.14mg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 0.05mg/norethindrone acetate 0.25mg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Aranelle	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing ethinylestradiol and norgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Lutera 28 tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol 600micrograms / norelgestromin 6mg transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing sodium estrone sulfate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol 2.5 microgram and norethisterone acetate 500 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing drospirenone and ethinylestradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely drospirenone 2 milligram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinyl estradiol 0.02mg / norelgestromin 0.15mg per day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Cyproterone acetate 2 mg and ethinylestradiol 35 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Cyproterone acetate+ethinyloestradiol	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing drospirenone and estradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely drospirenone 500 microgram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing ethinylestradiol and gestodene (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Ethinylestradiol (substance)	Is a	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol+norethisterone acetate 1mg/0.5mg tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing estradiol and norethisterone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing estradiol and levonorgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing estradiol and norgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
médicament contenant estradiol et acétate de médroxyprogestérone	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 500 microgram and norethisterone acetate 100 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 0.25mg/dose topical gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing dydrogesterone and estradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Estradiol 1.53mg transdermal spray	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 0.06mg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol 2 mg and norethisterone acetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)
Estradiol-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing estradiol in nasal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing estradiol in vaginal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topical estradiol allergy	Causative agent (attribute)	False	Estradiol	Inferred relationship	Existential restriction modifier (core metadata concept)	1

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Id	Description	Lang	Type	Status	Case?	Module
24201011	Estradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
730100013	Estradiol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3721927018	17-beta estradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3722984013	E2 - estradiol	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
24201011	Estradiol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
24201011	Estradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
473635011	Oestradiol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
473635011	Oestradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
730100013	Estradiol (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
730100013	Estradiol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1215921017	E2 - Oestradiol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1215922012	17-Beta oestradiol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1217424016	17-Beta estradiol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1217425015	E2 - Estradiol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
3721927018	17-beta estradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3722984013	E2 - estradiol	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
49321000195112	estradiolo	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
63461000195117	Estradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234641000195118	Östradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234651000195115	E2 - Estradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234661000195117	E>2< - Estradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
32701000188116	estradiol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
861191000172113	oestradiol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
32701000188116	estradiol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
861191000172113	oestradiol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
49321000195112	estradiolo	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
63461000195117	Estradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234641000195118	Östradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234651000195115	E2 - Estradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234661000195117	E>2< - Estradiol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module