Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Estradiol 4.167 microgram/hour prolonged-release vaginal ring |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 600 microgram/g cutaneous gel |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 600 microgram/g cutaneous gel |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 100 microgram/1 milliliter conventional release vaginal cream (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 100 microgram/1 milliliter conventional release vaginal cream (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 100mg implant (substance) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 100mg implant (substance) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 25 milligram/1 each prolonged-release subcutaneous implant (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 25 milligram/1 each prolonged-release subcutaneous implant (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 50 mg prolonged-release subcutaneous implant |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 50 mg prolonged-release subcutaneous implant |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 2.08 microgram/1 hour and norethisterone acetate 10.4 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely estradiol 2.08 microgram/1 hour and norethisterone acetate 10.4 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely estradiol 1.04 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 1.04 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 1.56 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 1.56 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 2.5 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 2.5 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 2.08 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 2.08 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 3.13 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 3.13 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 4.17 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
False |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 4.17 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
False |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 2.08 microgram/hour and norethisterone acetate 5.83 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 2.08 microgram/hour and norethisterone acetate 5.83 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 583 nanogram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 583 nanogram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing estradiol in subcutaneous dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing only estradiol in subcutaneous dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 1.88 microgram/hour and levonorgestrel 625 nanogram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 1.88 microgram/hour and levonorgestrel 625 nanogram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Polyestradiol phosphate |
Is modification of (attribute) |
False |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely elagolix sodium 300 milligram and estradiol 1 milligram and norethisterone 500 microgram/1 each conventional release oral capsule (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely elagolix sodium 300 milligram and estradiol 1 milligram and norethisterone 500 microgram/1 each conventional release oral capsule (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Elagolix- and estradiol- and norethisterone-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Elagolix and estradiol and norethisterone only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing only elagolix and estradiol and norethisterone in oral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Elagolix- and estradiol- and norethisterone-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol+norethisterone acetate 1mg/0.5mg tablet (substance) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol+norethisterone acetate 1mg/0.5mg tablet (substance) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely drospirenone 500 microgram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 500 microgram and norethisterone acetate 100 microgram oral tablet |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 500 microgram and norethisterone acetate 100 microgram oral tablet |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 2.083 microgram/hour and norethisterone acetate 7.083 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 2.083 microgram/hour and norethisterone acetate 7.083 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 2.083 microgram/hour and norethisterone acetate 10.417 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 2.083 microgram/hour and norethisterone acetate 10.417 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol and medroxyprogesterone only product in parenteral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol- and medroxyprogesterone-containing product in parenteral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely estradiol 10 microgram/1 each conventional release vaginal tablet (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely estradiol 10 microgram/1 each conventional release vaginal tablet (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 1 mg/g cutaneous gel |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 1 mg/g cutaneous gel |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Estradiol 1 mg and norethisterone acetate 1 mg oral tablet |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Estradiol 1 mg and norethisterone acetate 1 mg oral tablet |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Dydrogesterone and estradiol only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing dydrogesterone and estradiol in oral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Dydrogesterone 2.5 mg and estradiol 500 microgram oral tablet |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Dydrogesterone 2.5 mg and estradiol 500 microgram oral tablet |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely dydrogesterone 10 milligram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely dydrogesterone 10 milligram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely dydrogesterone 5 milligram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug) |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely dydrogesterone 5 milligram and estradiol 1 milligram/1 each conventional release oral tablet (clinical drug) |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Dydrogesterone 10 mg and estradiol 2 mg oral tablet |
Has precise active ingredient |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Dydrogesterone 10 mg and estradiol 2 mg oral tablet |
Has basis of strength substance (attribute) |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Fluid sample oestradiol level |
Component |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Plasma estradiol measurement |
Component |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Serum estradiol measurement |
Component |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Implantation of estradiol implant (procedure) |
Direct substance |
True |
Estradiol |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |