16058431000119104: White matter disease (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Head finding (finding)\Finding of brain\Disorder of brain\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Head finding (finding)\Finding of brain\Disorder of brain\Leukoencephalopathy\White matter disease (disorder)
\Head finding (finding)\Finding of head region\Leukoencephalopathy\White matter disease (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of brain\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Head finding (finding)\Disorder of head (disorder)\Disorder of brain\Leukoencephalopathy\White matter disease (disorder)

\Central nervous system finding\Finding of brain\Disorder of brain\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Central nervous system finding\Finding of brain\Disorder of brain\Leukoencephalopathy\White matter disease (disorder)
\Central nervous system finding\Disorder of the central nervous system (disorder)\Disorder of brain\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Central nervous system finding\Disorder of the central nervous system (disorder)\Disorder of brain\Leukoencephalopathy\White matter disease (disorder)
\Central nervous system finding\Disorder of the central nervous system (disorder)\Degenerative disease of the central nervous system\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Central nervous system finding\Disorder of the central nervous system (disorder)\Degenerative disease of the central nervous system\Demyelinating disease of central nervous system\White matter disease (disorder)

\Disease\Degenerative disorder\Degenerative disease of the central nervous system\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Disease\Degenerative disorder\Degenerative disease of the central nervous system\Demyelinating disease of central nervous system\White matter disease (disorder)
\Disease\Disorder of body system\Disease of nervous system (disorder)\Disorder of the central nervous system (disorder)\Disorder of brain\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Disease\Disorder of body system\Disease of nervous system (disorder)\Disorder of the central nervous system (disorder)\Disorder of brain\Leukoencephalopathy\White matter disease (disorder)
\Disease\Disorder of body system\Disease of nervous system (disorder)\Disorder of the central nervous system (disorder)\Degenerative disease of the central nervous system\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Disease\Disorder of body system\Disease of nervous system (disorder)\Disorder of the central nervous system (disorder)\Degenerative disease of the central nervous system\Demyelinating disease of central nervous system\White matter disease (disorder)
\Disease\Disorder of head (disorder)\Disorder of brain\Degenerative brain disorder\Cerebral degeneration (disorder)\White matter disease (disorder)
\Disease\Disorder of head (disorder)\Disorder of brain\Leukoencephalopathy\White matter disease (disorder)

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2017. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
White matter disease (disorder)	Is a	Demyelinating disease of central nervous system	true	Inferred relationship	Existential restriction modifier (core metadata concept)
White matter disease (disorder)	Is a	Disorder of brain	false	Inferred relationship	Existential restriction modifier (core metadata concept)
White matter disease (disorder)	Associated morphology	Demyelination	true	Inferred relationship	Existential restriction modifier (core metadata concept)	1
White matter disease (disorder)	Finding site	Cerebral white matter structure	true	Inferred relationship	Existential restriction modifier (core metadata concept)	1
White matter disease (disorder)	Is a	Leukoencephalopathy	true	Inferred relationship	Existential restriction modifier (core metadata concept)
White matter disease (disorder)	Is a	Cerebral degeneration (disorder)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Progressive multifocal leukoencephalopathy	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
Subcortical leukoencephalopathy (disorder)	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
Marchiafava-Bignami disease (disorder)	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
Onset of disease between 2 and 5 years of age with characteristics of cerebello-spastic syndrome exacerbated by episodes of fever or head trauma leading to death after 5 to 10 years of disease evolution, diffuse involvement of the white matter on cerebral MRI with a CSF-like signal intensity (cavitation), a recessive autosomal mode of inheritance, neuropathologic findings consistent with a cavitating orthochromatic leukodystrophy with increased number of oligodendrocytes. This disease is linked to mutations in the five EIF2B genes encoding the five subunits of the eukaryotic initiation factor 2B (eIF2B), involved in the protein synthesis and its regulation under cellular stress.	Is a	False	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
White matter disorder due to nutritional deficiency	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
Marburg acute multiple sclerosis	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
White matter disease due to microglioma	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)
White matter disease due to anti-phospholipid syndrome (disorder)	Is a	True	White matter disease (disorder)	Inferred relationship	Existential restriction modifier (core metadata concept)

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3431466015	White matter disease (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3431467012	White matter disease	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3431466015	White matter disease (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3431467012	White matter disease	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
5632661000241110	maladie de la substance blanche	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
5632661000241110	maladie de la substance blanche	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module