18288009: von Willebrand factor (substance)

SNOMED CT Concept\Substance\...

\Drug or medicament (substance)\Hematologic agent (substance)\Blood derivative (substance)\Coagulation related substance (substance)\...

\Intrinsic pathway of coagulation (substance)\von Willebrand factor

\Coagulation protein (substance)\von Willebrand factor

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein (substance)\von Willebrand factor

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein (substance)\von Willebrand factor

\Biological substance\Protein and/or protein derivative\Protein\Plasma protein (substance)\Coagulation protein (substance)\von Willebrand factor
\Biological substance\Blood derivative (substance)\Coagulation related substance (substance)\Intrinsic pathway of coagulation (substance)\von Willebrand factor
\Biological substance\Blood derivative (substance)\Coagulation related substance (substance)\Coagulation protein (substance)\von Willebrand factor
\Biological substance\Blood material\Blood component (substance)\Plasma protein (substance)\Coagulation protein (substance)\von Willebrand factor
\Biological substance\Haemostasis related substance\Coagulation related substance (substance)\Intrinsic pathway of coagulation (substance)\von Willebrand factor
\Biological substance\Haemostasis related substance\Coagulation related substance (substance)\Coagulation protein (substance)\von Willebrand factor
\Biological substance\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein (substance)\von Willebrand factor

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
von Willebrand factor	Is a	Intrinsic pathway of coagulation (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor	Is a	Coagulation protein (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor	Is a	Procoagulant	false	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor	Is a	Hematologic agent (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
von Willebrand factor ristocetin cofactor	Is a	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor multimer	Is a	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor antigen	Is a	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor antigen	Direct substance	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII R: R Co assay	Has measured component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII-related Willebrand factor assay (procedure)	Has measured component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor multimer assay	Has measured component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII R: Ag assay	Has measured component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII R: R Co assay	Component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Factor VIII-related Willebrand factor assay (procedure)	Component	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
von Willebrand factor multimer assay	Component	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII R: Ag assay	Component	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
von Willebrand factor products adverse reaction (disorder)	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor products allergy	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ristocetin 1.5 umol test (procedure)	Component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Ristocetin 0.5 umol test (procedure)	Component	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Factor VIII fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII by-passing fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Coagulation factor VIII- and von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII+von Willebrand factor 500iu/1100iu injection (pdr for recon)+diluent+kit (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII+von Willebrand factor 1000iu/2200iu injection (pdr for recon)+diluent+kit (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 500iu/von Willebrand factor 1250iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu/von Willebrand factor 2500iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII	Is a	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
von Willebrand factor products allergy	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII+von Willebrand factor 500iu/1100iu injection (pdr for recon)+diluent+kit (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII+von Willebrand factor 1000iu/2200iu injection (pdr for recon)+diluent+kit (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 500iu/von Willebrand factor 1250iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu/von Willebrand factor 2500iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII by-passing fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII fraction products adverse reaction	Causative agent (attribute)	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Coagulation factor VIII- and von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII 500iu/von Willebrand factor 1100iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu/von Willebrand factor 2200iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)
Von Willebrand factor adverse reaction	Causative agent (attribute)	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII and von Willebrand factor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
von Willebrand factor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing von Willebrand factor in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII and von Willebrand factor only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only von Willebrand factor in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	Has precise active ingredient	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	Has basis of strength substance (attribute)	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	Has precise active ingredient	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	Has basis of strength substance (attribute)	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII- and von Willebrand factor-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ristocetin 1.5 umol test (procedure)	Component	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ristocetin 0.5 umol test (procedure)	Component	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII R: R Co assay	Component	True	von Willebrand factor	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
30884011	von Willebrand factor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
30885012	Factor VIII vWF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
745687012	von Willebrand factor (substance)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1222088017	vWF- von Willebrand factor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
2668756016	von Willebrand factor ristocetin cofactor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
30884011	von Willebrand factor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
30885012	Factor VIII vWF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
30885012	Factor VIII vWF	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
30885012	Factor VIII vWF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
745687012	von Willebrand factor (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
745687012	von Willebrand factor (substance)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1222088017	vWF- von Willebrand factor	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1222088017	vWF- von Willebrand factor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
2668756016	von Willebrand factor ristocetin cofactor	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2668756016	von Willebrand factor ristocetin cofactor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
17291000188114	facteur de Willebrand	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
17291000188114	facteur de Willebrand	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module