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247573007: Intellectual ability (observable entity)


Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
369675010 Intellectual ability en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
637762013 Intellectual ability (observable entity) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
1224048011 Level of intelligence en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
369675010 Intellectual ability en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
369675010 Intellectual ability en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
637762013 Intellectual ability (observable entity) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core
637762013 Intellectual ability (observable entity) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
1224048011 Level of intelligence en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
1224048011 Level of intelligence en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core


5 descendants. Search Descendants:

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
Intellectual ability (observable entity) Is a Characteristic of intellect true Inferred relationship Existential restriction modifier (core metadata concept)

Inbound Relationships Type Active Source Characteristic Refinability Group
White matter hypoplasia, corpus callosum agenesis, intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Muscle eye brain disease with bilateral multicystic leukodystrophy Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
Hyperekplexia epilepsy syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Developmental delay, facial dysmorphism syndrome due to mediator complex subunit 13 like deficiency (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
21q22.11q22.12 microdeletion syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Intellectual disability, hyperkinetic movement, truncal ataxia syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
A rare genetic syndromic intellectual disability disorder with characteristics of variable degrees of intellectual disability, behavioral problems (including attention deficit and hyperactivity disorder, autism spectrum disorder, and aggressiveness) an altered sleeping pattern and delayed speech and language development associated with disruption of ankyrin 3 (ANK3 gene). Additional features observed may include muscular hypotonia and spasticity. Epilepsy, chronic hunger and dysmorphic facial features have been reported. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
14q32 deletion syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Mowat-Wilson syndrome due to monosomy 2q22 (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
X-linked complicated corpus callosum dysgenesis Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Contracture with ectodermal dysplasia and orofacial cleft syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 9
déficience intellectuelle liée à l'X type Brooks Interprets False Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
X-linked intellectual disability hypotonic face syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Angelman syndrome due to maternal monosomy 15q11q13 (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Polyhydramnios, megalencephaly, symptomatic epilepsy syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Microcephaly, corpus callosum and cerebellar vermis hypoplasia, facial dysmorphism, intellectual disability syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Brain malformations, musculoskeletal abnormalities, facial dysmorphism, intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Tall stature, intellectual disability, renal anomalies syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Congenital labioscrotal agenesis, cerebellar malformation, corneal dystrophy, facial dysmorphism syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Global developmental delay, neuro-ophthalmological abnormalities, seizures, intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Severe growth deficiency, strabismus, extensive dermal melanocytosis, intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
RERE-related neurodevelopmental syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Telomere maintenance 2-related intellectual disability, neurodevelopmental disorder (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Early-onset epilepsy, intellectual disability, brain anomalies syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
A rare X-linked syndromic intellectual disability characterized by intellectual disability of variable degree, behavioral anomalies (including autism, mood disorders, obsessive-compulsive behavior, and hetero- and auto-aggression), and epilepsy. Progressive neurological symptoms like movement disorders and spasticity, as well as subtle dysmorphic features have also been reported. Heterozygous females may be as severely affected as males. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
X-linked female restricted facial dysmorphism, short stature, choanal atresia, intellectual disability Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Recurrent metabolic encephalomyopathic crises, rhabdomyolysis, cardiac arrhythmia, intellectual disability syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Macrothrombocytopenia, lymphedema, developmental delay, facial dysmorphism, camptodactyly syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
Palatal anomalies, widely spaced teeth, facial dysmorphism, developmental delay syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Peripheral myelin protein 22-retinoic acid induced 1 contiguous gene duplication syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Combined oxidative phosphorylation defect type 23 Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Postnatal microcephaly, infantile hypotonia, spastic diplegia, dysarthria, intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
A rare genetic disease characterised by infantile onset of severe inflammatory bowel disease manifesting with bloody diarrhoea and failure to thrive, and central nervous system disease with global developmental delay and regression, impaired speech, hypotonia, hyperreflexia, and epilepsy. Brain imaging shows global cerebral atrophy, thin corpus callosum, delayed myelination, and posterior leucoencephalopathy. Cases with recurrent infections and impaired T-cell responses to stimulation, as well as decreased T-cell subsets, have been reported. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Intellectual disability, cardiac anomalies, short stature, joint laxity syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Gabriele-de Vries syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
GNB5-related intellectual disability, cardiac arrhythmia syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Growth delay, intellectual disability, hepatopathy syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Non-specific syndromic intellectual disability Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
STAG1-related intellectual disability, facial dysmorphism, gastrooesophageal reflux syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by variable developmental delay, intellectual disability, early-onset seizures, and facial dysmorphism (including arched eyebrows, long palpebral fissures, prominent nasal bridge, large ears, thin upper lip, and high arched palate). Other reported features are microcephaly, hypotonia, growth retardation, congenital heart defects, and malformations of the fingers and toes, as well as additional neurologic manifestations (such as ataxia or spastic quadriplegia). Brain imaging may show hypoplastic corpus callosum, white matter abnormalities, or cortical atrophy. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Witteveen Kolk syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Micrognathia, recurrent infections, behavioural abnormalities, mild intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Microcephalic cortical malformations, short stature due to rotatin deficiency (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Intellectual disability, epilepsy, extrapyramidal syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
WW domain containing adaptor with coiled-coil-related facial dysmorphism, developmental delay, behavioral abnormalities syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
VPS11-related autosomal recessive hypomyelinating leucodystrophy Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Seizures, scoliosis, macrocephaly syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Autosomal recessive complex spastic paraplegia due to Kennedy pathway dysfunction (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Short stature, brachydactyly, obesity, global developmental delay syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Spastic paraplegia, severe developmental delay, epilepsy syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Progressive spondyloepimetaphyseal dysplasia, short stature, short fourth metatarsals, intellectual disability syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
A rare multiple congenital anomalies/dysmorphic syndrome with intellectual disability, characterised by macrocephaly, intellectual disability, seizures, dysmorphic facial features (including tall forehead, downslanting palpebral fissures, hypertelorism, depressed nasal bridge, and macrostomia), megalencephaly, and small thorax. Other reported features are umbilical hernia, muscular hypotonia, global developmental delay, autistic behaviour, and café-au-lait spots, among others. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Macrocephaly, intellectual disability, left ventricular non compaction syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Basel Vanagaite Smirin Yosef syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Skeletal dysplasia, T-cell immunodeficiency, developmental delay syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Intellectual disability, seizures, abnormal gait, facial dysmorphism syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Congenital cerebellar ataxia due to RNA, U12 small nuclear mutation (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Severe neurodevelopmental disorder with feeding difficulties, stereotypic hand movement, bilateral cataract Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
Metopic ridging, ptosis, facial dysmorphism syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Dual specificity tyrosine phosphorylation regulated kinase 1A-related intellectual disability syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Chromodomain helicase dna-binding protein 3- related developmental delay, speech delay, intellectual disability, abnormalities of vision, facial dysmorphism syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Severe oculo-renal-cerebellar syndrome (disorder) Interprets False Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 10
Fryns Smeets Thiry syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
Progressive cerebello-cerebral atrophy (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
SATB2-associated syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Autosomal dominant deafness with onychodystrophy syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Agenesis of corpus callosum, macrocephaly, hypertelorism syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Severe intellectual disability, agenesis of corpus callosum, facial dysmorphism, cerebellar ataxia syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
Intellectual disability, muscle weakness, short stature, facial dysmorphism syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by variable developmental delay and intellectual disability, overweight or obesity, behavioral abnormalities (including hyperactivity, aggressive behavior, anxiety, mood disorder, or autistic features), and facial dysmorphism (such as high forehead, full eyebrows and/or synophrys, upturned nose, and fleshy ears, among others). Additional reported manifestations are hypotonia, ocular anomalies, anomalies of the fingers and toes, joint hypermobility, or abnormal pigmentation. Brain imaging may show mild nonspecific abnormalities. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
A rare autosomal ichthyosis syndrome with prominent neurologic signs characterized by the association of congenital ichthyosis with global developmental delay, intellectual disability, infantile-onset seizures, and spastic tetraplegia. Brain imaging may show delayed myelination and cerebral atrophy. Marked intrafamilial variability has been reported. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Cross syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 2
Microcephalus with brachydactyly and kyphoscoliosis syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 9
X-linked intellectual disability, cerebellar hypoplasia, spondyloepiphyseal dysplasia syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Craniofacial dysplasia, short stature, ectodermal anomalies, intellectual disability syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
A rare leukodystrophy characterized by a spectrum of progressive neurologic manifestations comprising rapidly progressive early-onset nystagmus, spastic tetraplegia, and visual and hearing impairment, resulting in death in early childhood, as well as later onset of slowly progressive complex spastic ataxia with pyramidal and cerebellar symptoms and loss of developmental milestones. Brain imaging shows diffuse hypomyelination of the subcortical and deep white matter, cerebellar atrophy, and diffuse spinal cord volume loss. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 10
Neurodevelopmental delay, seizures, ophthalmic anomalies, osteopenia, cerebellar atrophy syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
Intellectual disability, autism, speech apraxia, craniofacial dysmorphism syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Infantile hypotonia, oculomotor anomalies, hyperkinetic movements, developmental delay syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
QRICH1-related intellectual disability, chondrodysplasia syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Keppen Lubinsky syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
Pierpont syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Retinitis pigmentosa, juvenile cataract, short stature, intellectual disability syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Arginyl-tRNA synthetase 1-related autosomal recessive hypomyelinating leukodystrophy (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
SYNGAP1-related developmental and epileptic encephalopathy Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Prune exopolyphosphatase 1-related neurological syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4
Global developmental delay, alopecia, macrocephaly, facial dysmorphism, structural brain anomalies syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
3-methylglutaconic aciduria type 9 Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 3
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by the association of severe intellectual disability, strabismus, and anterior maxillary protrusion with vertical maxillary excess, open bite, and prominent crowded teeth. Mild cochlear hearing loss has been reported in addition. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 7
Neurodevelopmental disorder, craniofacial dysmorphism, cardiac defect, skeletal anomalies syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
9q33.3q34.11 microdeletion syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
16p13.2 microdeletion syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
A rare, X-linked, multiple congenital anomalies/dysmorphic malformation-intellectual disability syndrome characterized by developmental delay, mild to moderate intellectual disability, speech disturbance, behavioral problems (such as anxiety, hyperactivity, and aggressiveness) and mild facial dysmorphism (including facial hypotonia, thin arched eyebrows, ectropion, epicanthus, malar flatness, thick vermillion of the lips and prognathia). Additional variable manifestations include short stature, skeletal and genital anomalies, seizures, and autism spectrum disorders. Brain imaging may reveal cerebellar vermis hypoplasia, thin corpus callosum, and enlarged subarachnoid spaces. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
17q24.2 microdeletion syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
9q21.13 microdeletion syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 5
11q22.2q22.3 microdeletion syndrome Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
19p13.3 microduplication syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
20q11.2 microdeletion syndrome (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
A multiple congenital anomalies/dysmorphic - intellectual disability syndrome characterized by feeding problems, growth retardation, microcephaly, developmental delay, digital and vertebral anomalies, joint laxity/dislocation, cardiac and renal defects, and dysmorphic facial features (including plagiocephaly, prominent forehead, bitemporal narrowing, bilateral coloboma, epicanthal folds, malformations of the outer and middle ear, wide nasal bridge, anteverted nares, prominent and bulbous nose tip, long philtrum, thin lips, high and narrow palate, micrognathia with prognathism/retrognathism, full cheeks, and short, broad neck). Additional variable manifestations include obstructive apneas, recurrent pneumonia, and seizures. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
Megaconial congenital muscular dystrophy (disorder) Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 6
A rare genetic syndromic neurodevelopmental disorder with characteristics of moderate to mostly severe intellectual disability, speech impairment with normal or mildly delayed motor development and early-onset seizures often accompanied by developmental regression. Autistic behaviour and stereotypic movements are common. The disorder is caused by bi-allelic intragenic deletions (rarely duplications) or truncating variants in the CNTNAP2 gene (7q35-q36.1). It encodes contactin-associated protein 2 (CASPR2), a transmembrane protein from the neurexin superfamily, which is involved in neural-glia interactions and clustering of potassium channels in myelinated axons. Inheritance is autosomal recessive. Interprets True Intellectual ability (observable entity) Inferred relationship Existential restriction modifier (core metadata concept) 4

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