255641001: Caffeine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Substance with hydrolase inhibitor mechanism of action (substance)\Phosphodiesterase inhibitor\Caffeine

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Purine and/or purine derivative\Xanthine and/or xanthine derivative (substance)\Xanthine derivative (substance)\Methyl xanthine\Caffeine

\Substance categorized functionally\Phytochemical\Caffeine

\Material (substance)\Natural material\Organic natural material\Plant material (substance)\Phytochemical\Caffeine

\Biological substance\Organic natural material\Plant material (substance)\Phytochemical\Caffeine

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Caffeine	Is a	Phytochemical	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Xanthine	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Central nervous system agent (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	allergène médicamenteux	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Methyl xanthine	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Central respiratory stimulant	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Phosphodiesterase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Has disposition	Phosphodiesterase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine	Is a	Psychostimulant	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Acetaminophen+butalbital+caffeine 325mg/50mg/40mg capsule	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Acetaminophen+butalbital+caffeine 500mg/50mg/40mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Acetaminophen+butalbital+caffeine 500mg/50mg/40mg tablet	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely caffeine 100 milligram and ergotamine tartrate 1 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely caffeine 100 milligram and ergotamine tartrate 1 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine 25 mg and paracetamol 450 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine 25 mg and paracetamol 450 mg oral tablet	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Butalbital 50 mg and caffeine 40 mg and codeine phosphate 30 mg and paracetamol 325 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Butalbital 50 mg and caffeine 40 mg and codeine phosphate 30 mg and paracetamol 325 mg oral capsule	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Aspirin 385 mg and caffeine 30 mg and orphenadrine citrate 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aspirin 385 mg and caffeine 30 mg and orphenadrine citrate 25 mg oral tablet	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely caffeine 60 milligram and dihydrocodeine tartrate 32 milligram and paracetamol 712.8 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely caffeine 60 milligram and dihydrocodeine tartrate 32 milligram and paracetamol 712.8 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Acetaminophen+butalbital+caffeine 325mg/50mg/40mg capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Acetaminophen+butalbital+caffeine 325mg/50mg/40mg capsule	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 325 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 325 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 500 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 500 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely aspirin 389 milligram and caffeine 32.4 milligram and dextropropoxyphene hydrochloride 32 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Caffeine 65 mg and paracetamol 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine 65 mg and paracetamol 500 mg oral tablet	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely caffeine 30 milligram and paracetamol 450 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely caffeine 30 milligram and paracetamol 450 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 325 milligram and butalbital 50 milligram and caffeine 40 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aspirin 325 milligram and butalbital 50 milligram and caffeine 40 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aspirin 389 mg and caffeine 32.4 mg and dextropropoxyphene hydrochloride 65 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aspirin 389 mg and caffeine 32.4 mg and dextropropoxyphene hydrochloride 65 mg oral capsule	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 325 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Acetaminophen+butalbital+caffeine 500mg/50mg/40mg tablet	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 389 milligram and caffeine 32.4 milligram and dextropropoxyphene hydrochloride 32 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 389 milligram and caffeine 32.4 milligram and dextropropoxyphene hydrochloride 32 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely caffeine 100 milligram and ergotamine tartrate 1 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aspirin + butalbital + caffeine 325mg/50mg/40mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aspirin + butalbital + caffeine 325mg/50mg/40mg tablet	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 356.4 milligram and caffeine 30 milligram and dihydrocodeine tartrate 16 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 356.4 milligram and caffeine 30 milligram and dihydrocodeine tartrate 16 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine 30 mg and dihydrocodeine tartrate 16 mg and paracetamol 356.4 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Caffeine 30 mg and dihydrocodeine tartrate 16 mg and paracetamol 356.4 mg oral capsule	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aspirin 250 milligram and caffeine 65 milligram and paracetamol 250 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 250 milligram and caffeine 65 milligram and paracetamol 250 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 325 milligram and butalbital 50 milligram and caffeine 40 milligram and codeine phosphate 30 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aspirin 856 mg and caffeine 60 mg and orphenadrine citrate 50 mg oral tablet	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely aspirin 250 milligram and caffeine 65 milligram and paracetamol 250 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Caffeine monohydrate (substance)	Is a	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine hydrate (substance)	Is a	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Management of caffeine intake	Direct substance	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine citrate (substance)	Is modification of (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeinated coffee	Is modification of (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine hydrate (substance)	Is modification of (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeine monohydrate (substance)	Is modification of (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Caffeinated soft drinks	Is modification of (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing caffeine and codeine and paracetamol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing caffeine and codeine and paracetamol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Acetaminophen 300 mg and caffeine 15 mg and codeine phosphate 30 mg oral tablet	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine 15 mg and codeine phosphate 15 mg and paracetamol 300 mg oral tablet	Has basis of strength substance (attribute)	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Caffeine- and sodium benzoate-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Ergotamine tartrate+caffeine 2mg/100mg suppository (substance)	Has basis of strength substance (attribute)	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ergotamine tartrate+caffeine 2mg/100mg suppository (substance)	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing caffeine and ergotamine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 325 milligram and butalbital 50 milligram and caffeine 40 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aspirin 385 mg and caffeine 30 mg and orphenadrine citrate 25 mg oral tablet	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing aspirin and caffeine and paracetamol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aspirin 389 mg and caffeine 32.4 mg and dextropropoxyphene hydrochloride 65 mg oral capsule	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aspirin 389 milligram and caffeine 32.4 milligram and dextropropoxyphene hydrochloride 32 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing aspirin and butalbital and caffeine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing aspirin and butalbital and caffeine and codeine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing aspirin and caffeine and orphenadrine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aspirin- and caffeine- and dihydrocodeine-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing aspirin and caffeine and dihydrocodeine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely caffeine 100 milligram and ergotamine tartrate 1 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aspirin 325 milligram and butalbital 50 milligram and caffeine 40 milligram and codeine phosphate 30 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aspirin- and butalbital- and caffeine- and codeine-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 356.4 milligram and caffeine 30 milligram and dihydrocodeine tartrate 16 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Aspirin 856 mg and caffeine 60 mg and orphenadrine citrate 50 mg oral tablet	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Caffeine 30 mg and dihydrocodeine tartrate 16 mg and paracetamol 356.4 mg oral capsule	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aspirin + butalbital + caffeine 325mg/50mg/40mg tablet	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 770 milligram and caffeine 60 milligram and orphenadrine citrate 50 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely caffeine 60 milligram and dihydrocodeine tartrate 32 milligram and paracetamol 712.8 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Caffeine 15 mg and codeine phosphate 15 mg and paracetamol 300 mg oral tablet	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely caffeine 30 milligram and paracetamol 450 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine 25 mg and paracetamol 450 mg oral tablet	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Acetaminophen 300 mg and caffeine 15 mg and codeine phosphate 30 mg oral tablet	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aspirin 250 milligram and caffeine 65 milligram and paracetamol 250 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Caffeine 65 mg and paracetamol 500 mg oral tablet	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 500 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Butalbital 50 mg and caffeine 40 mg and codeine phosphate 30 mg and paracetamol 325 mg oral capsule	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Aspirin 428 mg and caffeine 30 mg and orphenadrine citrate 25 mg oral tablet	Has precise active ingredient	False	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely butalbital 50 milligram and caffeine 40 milligram and paracetamol 325 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Acetaminophen+butalbital+caffeine 500mg/50mg/40mg tablet	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing butalbital and caffeine and codeine and paracetamol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing butalbital and caffeine and codeine and paracetamol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing caffeine and dihydrocodeine and paracetamol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing caffeine and dihydrocodeine and paracetamol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Acetaminophen+butalbital+caffeine 325mg/50mg/40mg capsule	Has precise active ingredient	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing caffeine and isometheptene and paracetamol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aspirin- and caffeine- and dextropropoxyphene-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing butalbital and caffeine and paracetamol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine- and ergotamine-containing product in rectal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Caffeine- and paracetamol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing aspirin and caffeine and dextropropoxyphene (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Caffeine	Inferred relationship	Existential restriction modifier (core metadata concept)	1

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Id	Description	Lang	Type	Status	Case?	Module
380891010	Caffeine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
646709011	Caffeine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
380891010	Caffeine	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
380891010	Caffeine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
646709011	Caffeine (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
646709011	Caffeine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
56441000195115	caffeina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71441000195114	Coffein	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
659461000274116	Koffein	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
796671000172110	caféine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
796671000172110	caféine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
56441000195115	caffeina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71441000195114	Coffein	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
659461000274116	Koffein	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module