278910002: Coagulation factor VIII (substance)

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein (substance)\Factor VIII

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Plasma protein (substance)\Coagulation protein (substance)\Factor VIII

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Factor VIII	Is a	Intrinsic pathway of coagulation (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII	Is a	von Willebrand factor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII	Is a	Coagulation protein (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII	Is a	Intrinsic pathway of coagulation (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Coagulation factor VIIIa	Is a	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 250iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 500iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing high purity factor VIII	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
High purity factor VIII fraction 250iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
High purity factor VIII fraction 500iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
High purity factor VIII fraction 1000iu injection (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
High purity factor VIII fraction 350iu powder for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 250iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 500iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII fraction products (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Coagulation factor VIII- and von Willebrand factor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Factor VIII+von Willebrand factor 500iu/1100iu injection (pdr for recon)+diluent+kit (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII+von Willebrand factor 1000iu/2200iu injection (pdr for recon)+diluent+kit (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
DNA factor VIII (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Intermediate factor VIII	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing porcine factor VIII (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII by-passing fraction products (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII by-passing fraction 500iu injection (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII by-passing fraction 1000iu injection (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Intermediate factor VIII fraction 250iu injection (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Intermediate factor VIII fraction 500iu injection (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Porcine factor VIII 700iu injection (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Coagulation factor VIII-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII 500iu/von Willebrand factor 1250iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu/von Willebrand factor 2500iu powder for injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Octocog alfa (substance)	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Porcine factor VIII (substance)	Is a	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII fraction products adverse reaction	Causative agent (attribute)	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII by-passing fraction products adverse reaction	Causative agent (attribute)	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII fraction products allergy	Causative agent (attribute)	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to anti-inhibitor coagulant complex (finding)	Causative agent (attribute)	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Antihemophilic factor transfusion (procedure)	Direct substance	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Antihemophilic factor transfusion (procedure)	Direct substance	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Moroctocog alfa (substance)	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to anti-inhibitor coagulant complex (finding)	Causative agent (attribute)	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Factor VIII fraction products allergy	Causative agent (attribute)	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Simoctocog alfa (substance)	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Efmoroctocog alfa (substance)	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Turoctocog alfa (substance)	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Lonoctocog alfa	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 500iu/von Willebrand factor 1100iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII 1000iu/von Willebrand factor 2200iu powder for conventional release solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Factor VIII adverse reaction	Causative agent (attribute)	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor II and coagulation factor IX and coagulation factor VIIa and coagulation factor VIII and coagulation factor X only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only coagulation factor VIII (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII and von Willebrand factor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Susoctocog alfa (substance)	Is a	False	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)
Coagulation factor VIII and von Willebrand factor only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	Has basis of strength substance (attribute)	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Coagulation factor VIII 1000 unit and von Willebrand factor 2500 unit powder for solution for injection vial	Has precise active ingredient	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	Has basis of strength substance (attribute)	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Coagulation factor VIII 500 unit and von Willebrand factor 1250 unit powder for solution for injection vial	Has precise active ingredient	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Coagulation factor VIII- and von Willebrand factor-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely coagulation factor VIII 500 unit/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely coagulation factor VIII 500 unit/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII 250 unit powder for solution for injection vial	Has precise active ingredient	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII 250 unit powder for solution for injection vial	Has basis of strength substance (attribute)	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely coagulation factor VIII 1000 unit/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely coagulation factor VIII 1000 unit/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Coagulation factor VIII only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing coagulation factor VIII in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Factor VIII	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
415960013	Antihaemophilic factor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415961012	Antihaemophilic globulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415962017	Antihaemophilic factor A	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415963010	Coagulation factor VIII	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415964016	AHG	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415965015	Factor VIII	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415966019	AHF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415967011	Platelet cofactor I	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415968018	Antihemophilic factor A	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415969014	Antihemophilic factor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415970010	Antihemophilic globulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4042397014	Coagulation factor VIII (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415960013	Antihaemophilic factor	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415960013	Antihaemophilic factor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415961012	Antihaemophilic globulin	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415961012	Antihaemophilic globulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415962017	Antihaemophilic factor A	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415963010	Coagulation factor VIII	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415964016	AHG	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415965015	Factor VIII	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415965015	Factor VIII	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415966019	AHF	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
415967011	Platelet cofactor I	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415968018	Antihemophilic factor A	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415969014	Antihemophilic factor	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415969014	Antihemophilic factor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
415970010	Antihemophilic globulin	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
415970010	Antihemophilic globulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
672127012	Factor VIII (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
672127012	Factor VIII (substance)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
672127012	Factor VIII (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
4042397014	Coagulation factor VIII (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
237041000195117	fattore VIII di coagulazione	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
236211000195110	Blutgerinnungsfaktor VIII	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
6914461000241113	facteur VIII de coagulation	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
42841000188110	facteur VIII de coagulation humain	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
6914461000241113	facteur VIII de coagulation	fr	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
237041000195117	fattore VIII di coagulazione	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
236211000195110	Blutgerinnungsfaktor VIII	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module