Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
A rare neurodegenerative disease usually presenting before the age of 30 and which is characterized by dystonia, L-dopa-responsive parkinsonism, pyramidal signs and rapid cognitive decline. |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Brain calcification Rajab type (disorder) |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Craniosynostosis and intracranial calcification syndrome |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Brain calcification Rajab type (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Huntington disease-like syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare severe neurodegenerative disorder that is considered one of the phenocopies of Huntington Disease (HD) affecting patients of African descent and characterized by a triad of movement (chorea, oculomotor, parkinsonism), psychiatric (prominently sadness, irritability and anxiety), and cognitive abnormalities (early cognitive decline and subcortical-like dementia). |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism co-occurrent and due to acute infection (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Parkinsonism due to human immunodeficiency virus infection (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism following infection (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Parkinsonism due to hereditary spastic paraplegia (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Infantile dystonia parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Atypical Parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism due to heredodegenerative disorder (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Kufor Rakeb syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
McLeod neuroacanthocytosis syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypomyelinating leukodystrophy with atrophy of basal ganglia and cerebellum (disorder) |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
7 |
Atypical juvenile parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Infection causing parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Sporadic Parkinson disease |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism due to and following injury of head |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Parkinsonism due to mass lesion of brain (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Chorea co-occurrent and due to Huntington disease-like condition (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Functional parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Corticobasal degeneration |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Hemiparkinsonism hemiatrophy syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Traumatic haemorrhage of basal ganglia |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Traumatic haemorrhage of basal ganglia |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Parkinsonism caused by cyanide (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypomyelinating leukodystrophy with atrophy of basal ganglia and cerebellum (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
X-linked parkinsonism with spasticity syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Huntington disease-like 3 |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Pettigrew syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Craniosynostosis and intracranial calcification syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Huntington disease-like syndrome due to chromosome 9 open reading frame 72 expansions (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare genetic human prion disease characterised by adult-onset neurodegenerative manifestations associated with a movement disorder and psychiatric/behavioural disturbances. Patients typically present personality changes, aggressiveness, manias, anxiety and/or depression in conjunction with rapidly progressive cognitive decline (presenting with dysarthria, apraxia, aphasia and eventually leading to dementia) as well as ataxia (manifesting with gait disturbances, unsteadiness, coordination problems), Parkinsonism, myoclonus, and/or chorea. Additional features may include generalised spasticity, seizures, urine incontinence and pyramidal abnormalities. There is evidence the disease is caused by 8 extra octapeptide repeats in the PRNP gene on chromosome 20p13. |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonian pyramidal syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Calcification of basal ganglia (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Dissociative neurological symptom disorder co-occurrent with parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare neuronal ceroid lipofuscinosis disorder with characteristics of juvenile-onset progressive spinocerebellar ataxia, bulbar syndrome (manifesting with dysarthria, dysphagia and dysphonia), pyramidal and extrapyramidal involvement (including myoclonus, amyotrophy, unsteady gait, akinesia, rigidity, dysarthric speech) and intellectual deterioration. Muscle biopsy displays autofluorescent bodies and lipofuscin deposits in brain and occasionally the retina upon post mortem. |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Amyotrophic lateral sclerosis, parkinsonism, dementia complex (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Fahr's syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Parkinsonism caused by neuroleptic drug (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by methanol (disorder) |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Parkinsonism caused by carbon disulfide (disorder) |
Finding site |
False |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Traumatic haemorrhage of basal ganglia |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cerebrovascular accident of basal ganglia (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Autosomal recessive familial Parkinson disease |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Progressive supranuclear palsy parkinsonism syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
MPTP-induced parkinsonism |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Carbon monoxide-induced parkinsonism (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Manganese-induced parkinsonism |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by carbon disulfide (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by drug (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by methanol (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
On - off phenomenon (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Psychosis co-occurrent and due to Parkinson's disease (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Childhood-onset basal ganglia degeneration syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism following Mycoplasma infection (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Parkinsonism due to prion disease (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Structure of cerebral nucleus (body structure) |
Is a |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Toxin-induced parkinsonism |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by pesticide (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Aicardi Goutieres syndrome type 1 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Aicardi Goutieres syndrome type 2 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Aicardi Goutieres syndrome type 3 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Aicardi Goutieres syndrome type 4 |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Aicardi Goutieres syndrome type 5 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tubulinopathy-associated dysgyria (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Severe oculo-renal-cerebellar syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
Corticobasal syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare clinical situation occurring in the context of Parkinson disease characterized by return or worsening of symptoms (including motor and/or non-motor symptoms) under antiparkinsonian therapy. Types of off-periods are Morning Off (experienced before the first dose of the day), Delayed On (occurring more frequently after the first dose of the day or after meals), Wearing Off (end-of-dose deterioration), Sudden Off (sudden transition from on to off), and Dose Failure. |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Mitochondrial enoyl coenzyme A reductase protein-associated neurodegeneration syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Amyotrophic lateral sclerosis with parkinsonism |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Amyotrophic lateral sclerosis, parkinsonism, dementia complex of Kii Peninsula |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Amyotrophic lateral sclerosis, parkinsonism, dementia complex of West New Guinea (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Chorea due to Huntington disease-like 3 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Chorea due to Huntington disease-like 2 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Chorea due to Huntington disease-like 1 (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Hemichorea due to injury of head (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hemichorea due to cerebral arteriovenous malformation (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hemichorea due to brain abscess |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hemichorea due to cerebral hemorrhage |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by dopamine receptor antagonist (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Parkinsonism caused by dopamine depleting agent (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hemichorea due to neoplasm of brain (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hemichorea due to cerebral infarction |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hemichorea due to multiple sclerosis (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Oral choreiform movement |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Chorea due to neuroferritinopathy |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Dentatorubropallidoluysian degeneration |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Henoch's chorea |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Wilson's disease |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
Rheumatic chorea with heart involvement |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Dubini's chorea |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Chorea gravidarum |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Birnbaum's syndrome (disorder) |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Rheumatic chorea |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Chronic progressive non-hereditary chorea |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Rheumatic chorea without heart involvement |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Westphal-Strumpell syndrome |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
Benign hereditary chorea |
Finding site |
True |
Basal ganglion structure (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |