Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Maternal obesity complicating pregnancy, childbirth and the puerperium, antepartum |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Generalized obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Fat pad syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Central obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Morbid obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Obesity by adipocyte growth pattern (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay syndrome is characterised by precocious obesity, congenital hypothyroidism, neonatal colitis, cardiac hypertrophy, craniosynostosis and developmental delay. It has been described in two brothers, one of whom died within the first month of life. The parents of the two children were nonconsanguineous and in good health, however, the pregnancies were complicated by a maternal HELLP syndrome (Haemolysis, Elevated Liver enzymes and Low Platelets). The mode of inheritance has not yet been clearly established. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
Hydrocephalus with obesity and hypogonadism syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
obésité selon l'âge d'apparition |
Interprets |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Obesity by contributing factors (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hyperplastic obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare genetic endocrine disease characterized by early onset of severe intractable diarrhea and intestinal malabsorption, followed by obesity and hormonal deficiencies due to insufficient activation of several prohormones, resulting in hypocortisolism, hypothyroidism, diabetes insipidus, hypogonadism, growth deficiency, and diabetes mellitus. Extent and age of onset of hormone deficiencies are variable between patients. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypothyroid obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Macrocephaly, obesity, mental disability, ocular abnormality syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
gain pondéral excessif durant la grossesse |
Interprets |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Drug-induced obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Steatopygia |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Obesity by fat distribution pattern (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypothalamic obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Childhood obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Severe obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Intellectual disability, obesity, brain malformation, facial dysmorphism syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Wilson-Turner syndrome (WTS) is a very rare X-linked multisystem genetic disease characterized by intellectual disability, truncal obesity, gynecomastia, hypogonadism, dysmorphic facial features, and short stature. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Obesity due to melanocortin 4 receptor deficiency (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Extreme obesity with alveolar hypoventilation |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Endogenous obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Severe obesity complicating pregnancy |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Adiposogenital dystrophy (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Mauriac's syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Hyperinsulinar obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Android obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Constitutional obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Lifelong obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypertrophic obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Familial obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypogonadal obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
X-linked intellectual disability with precocious puberty and obesity syndrome |
Interprets |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Adult-onset obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
MEHMO syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Obesity of endocrine origin |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Gynaecoid obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Proopiomelanocortin deficiency syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypertrophy of fat pad of knee |
Interprets |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Obesity caused by energy imbalance (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Peripheral obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Localized obesity (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
MORM syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Simple obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Prader-Willi-like syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Intellectual disability, seizures, macrocephaly, obesity syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Rapid-onset childhood obesity, hypothalamic dysfunction, hypoventilation, autonomic dysregulation syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Intellectual disability, obesity, prognathism, eye and skin anomalies syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Colobomatous microphthalmia, obesity, hypogenitalism, intellectual disability syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Self reported body weight |
Is a |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Obesity due to CEP19 deficiency |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Severe early-onset obesity insulin resistance syndrome due to SH2B adaptor protein 1 deficiency (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
A rare genetic non-syndromic obesity disease with characteristics of severe early-onset obesity associated with major hyperphagia and endocrine abnormalities resulting from leptin receptor deficiency. Caused by homozygous mutation in the gene encoding the leptin receptor (LEPR) on chromosome 1p31. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Hypertrophy of fat pad of right knee (disorder) |
Interprets |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Hypertrophy of fat pad of left knee |
Interprets |
False |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Obesity in adolescence (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Obese class III |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
High body weight (finding) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare genetic form of obesity with characteristics of severe early-onset obesity, hyperphagia and variable presence of cognitive impairment and behavioural disorder, including autistic spectrum behaviour, impaired concentration and memory deficit. Some patients present with Prader-Willi-like features such as hypotonia, developmental delay, intellectual disability, short stature, hypopituitarism and dysmorphic facial features. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
6q16 microdeletion syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Pre-amputation measured body weight |
Is a |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Obesity due to pituitary disease |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by variable developmental delay and intellectual disability, overweight or obesity, behavioral abnormalities (including hyperactivity, aggressive behavior, anxiety, mood disorder, or autistic features), and facial dysmorphism (such as high forehead, full eyebrows and/or synophrys, upturned nose, and fleshy ears, among others). Additional reported manifestations are hypotonia, ocular anomalies, anomalies of the fingers and toes, joint hypermobility, or abnormal pigmentation. Brain imaging may show mild nonspecific abnormalities. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
SIM1-related Prader-Willi-like syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
MAGE family member L2-related Prader-Willi-like syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
X-linked intellectual disability-short stature-overweight syndrome is a multiple congenital anomalies syndrome characterised by borderline to severe intellectual disability, speech delay, short stature, elevated body mass index, a pattern of truncal obesity (reported in older males), and variable neurologic features (e.g. hypotonia, tremors, gait disturbances, behavioural problems, and seizure disorders). Less common manifestations include microcephaly, microorchidism and/or microphallus. Dysmorphic features have been reported in some patients but no consistent pattern has been noted. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
6 |
Spastic paraplegia, intellectual disability, nystagmus, obesity syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Genetic non-syndromic obesity |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Congenital leptin deficiency |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Clark Baraitser syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
A rare neurodevelopmental syndrome characterised by developmental delay, intellectual disability of varying severity and weight disorders (overweight/obesity and eating behaviour disorders including hyperphagia, tachyphagia, food impulsiveness and a feeling of permanent hunger). Additional clinical features include learning difficulties (may be combined with dysphasia, dyspraxia, dyscalculia, dysgraphia), severe language delay, behavioural disorders (stereotypies, impulsiveness or intolerance to frustration, self or hetero aggression, autism spectrum disorder) and non-specific dysmorphism. Epilepsy and ophthalmologic abnormalities can also be observed. Endocrine abnormalities are rarely associated. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Early-onset obesity, hyperphagia, severe developmental delay syndrome |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare Prader-Willi-like syndrome with characteristics of intellectual disability, morbid obesity, hypogonadotrophic hypogonadism, hyperphagia and developmental delay. Endocrine disorders including hypothyroidism and insulin resistance can be observed. Unlike Prader-Willi syndrome, profound muscular hypotonia, feeding difficulties in neonates, short stature and growth hormone deficiency are not observed. |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
6 |
Developmental delay, overweight, facial dysmorphism, behavioral abnormalities syndrome (disorder) |
Interprets |
True |
Measured body weight (observable entity) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |