Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
pT3a,b: Tumor invades through the muscularis propria into the subserosa or into non-peritonealized pericolic or perirectal tissues, invades 5 mm or less beyond the border of the muscularis propria (colon/rectum) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Non-viable tumor present in specimen |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T3: Aerodigestive tract tumor invades any of the following: bone of posterior wall of maxillary sinus, subcutaneous tissues, skin of cheek, floor or medial wall of orbit, infratemporal fossa, pterygoid plates, ethmoid sinuses |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2: Tumor more than 2 cm but not more than 4 cm in greatest dimension limited to the thyroid (thyroid) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
International neuroblastoma pathology classification: Favorable histology group, patient less than 1.5 years of age, with poorly differentiated neuroblastoma (Schwannian stroma-poor), and low or intermediate mitosis-karyorrhexis index |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
G4: Nuclei bizarre and multilobated, 20 µ or greater, nucleoli prominent, chromatin clumped |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT1a (IA): Invasive carcinoma diagnosed only by microscopy. All macroscopically visible lesions (even with superficial invasion) are pT1b/IB (TNM category and FIGO stage) (uterine cervix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
WHO grade IV (central nervous system tumor) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Modified Dukes stage C1 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
International Federation of Gynecology and Obstetrics vulvar melanoma stage III |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumour invasion of periprostatic fat absent (prostate) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT1a: Tumor 5 cm or less in greatest dimension, superficial tumor (extraosseous primitive neuroectodermal tumor/Ewing's sarcoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Papillary tumour configuration |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Gleason grade finding for prostatic cancer (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
M1a: non-regional lymph node metastasis |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T1: Tumor invades lamina propria or submucosa |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
N1b: 4-7 nodes involved |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Intergroup rhabdomyosarcoma study post-surgical clinical group IIA: localized tumor, gross total resection, but with microscopic residual disease |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Hemorrhagic tumor (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pN1: Metastasis with a lymph node mass 2 cm or less in greatest dimension and less than or equal to 5 nodes positive, none more than 2 cm in greatest dimension (testis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor nodule site cannot be assessed (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T3: Stomach tumor penetrates serosa without invasion of adjacent structures |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
G2: 6-50 percent non-squamous solid growth (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tis (0): Carcinoma in situ (limited to fallopian tube mucosa) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor site indeterminate |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Extrascleral tumor extension present (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2: Tumor invades mucosa of more than one adjacent subsite of supraglottis or glottis or region outside the supraglottis (e.g., mucosa of base of tongue, vallecula, medial wall of pyriform sinus) without fixation of the larynx |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pN1: Metastasis in a single lymph node, 2 cm or less in greatest dimension (urinary bladder, ureter, renal pelvis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
International Federation of Gynecology and Obstetrics cervical cancer stage II |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Microcalcifications in tumor present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
N2: Metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT3b: Tumor invades perivesical tissue macroscopically (extravesical mass) (urinary bladder) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT0 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T1: Aerodigestive tract tumor confined to nasopharynx |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor stage finding (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT1b1 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Finding addressing invasion of optic nerve by tumor (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT1: Tumor limited to one subsite of supraglottis with normal vocal cord mobility (larynx, supraglottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Finding addressing invasion of sclera by tumor (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT2: Tumor more than 5 cm in greatest dimension (extraosseous primitive neuroectodermal tumor/Ewing's sarcoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T4 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT4: Tumor involves any of the ipsilateral pleural surfaces plus additional sites as by American Joint Committee on Cancer 6th Edition definition (thoracic mesothelioma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
N3: Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene or supraclavicular lymph node(s) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
No primary site synchronous tumors present (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2: Tumor extends to the supraglottis AND/OR subglottis, AND/OR with impaired vocal cord mobility (larynx, glottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor infiltration by lymphocytes present (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumour invasion into bronchus, in situ |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Epithelial ovarian tumor, International Federation of Gynecology and Obstetrics stage IIIC |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Grade not determined (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT2: Minimal invasion of the optic nerve and/or optic coats (retinoblastoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Upper aerodigestive tract TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumour grade G0 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT4: Invasion of bladder AND/OR rectum (prostate) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor stage T3a |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Fallopian tube TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T1: Solitary liver tumor < 2 cm; no vascular invasion |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2b (IIB): Tumor with parametrial invasion (TNM category and FIGO stage) (uterine cervix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Node stage N1biii |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pTis: Carcinoma in situ (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor invades beyond pancreatic capsule to duodenum (endocrine pancreas) (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Involvement of tumor by anaplasia indeterminate (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Lip and oral cavity TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2: Tumor invading two subsites in a single region or extending to involve an adjacent region within the nasoethmoidal complex, with or without bony invasion (nasal cavity and ethmoid sinus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Stage IV: Distant metastasis or extension into other organs (adrenal cortical carcinoma) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2a: Tumor more than 5 cm in greatest dimension, superficial tumor (extraosseous primitive neuroectodermal tumor/Ewing's sarcoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT3a: Tumor directly invades adrenal gland or perirenal and/or renal sinus fat but not beyond Gerota's fascia (kidney) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Malignant chylothorax (disorder) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT1: Tumor confined to the retina, vitreous, or subretinal space. No optic nerve or choroidal invasion (retinoblastoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT2b: Tumor more than 5 cm in greatest dimension, deep tumor (extraosseous primitive neuroectodermal tumor/Ewing's sarcoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Radiologic infiltrate |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Lymphoma stage Ie |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pN3: Metastasis in perirectal and inguinal lymph nodes AND/OR bilateral internal iliac AND/OR inguinal lymph nodes (anal canal) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Raised tumour |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT1c: Tumor limited to the iris with melanomalytic glaucoma (iris) (uveal melanoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Scleral stage SX |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Seminal vesicle absent in tumour specimen |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor stage T3b |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Abnormal radiologic density, large area |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
No tumor invasion |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
International Federation of Gynecology and Obstetrics vulvar carcinoma (FIGO VC) stage IA |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T3 (III): Vaginal tumor extends to pelvic wall |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Sentinel conjunctival vessel |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT1: Tumor 2 cm or less in greatest dimension (anal canal) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor site not applicable |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pM1 (IVB): Distant metastasis (TNM category and FIGO stage) (vagina) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Exocrine pancreas TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor stage T2a |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Uterus and uterine adnexa involved by direct extension of malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Seminoma of testis, stage 2 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT3: Tumor involves bony structures and/or paranasal sinuses (nasopharynx) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Small tumor |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pN1b category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T2: Renal tumor > 7.0 cm in greatest dimension limited to the kidney |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Renal tumor finding (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Infiltrating tumor border |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
pT3 and/or N1 (III): Tumor involves one or both fallopian tubes, with peritoneal implants outside the pelvis AND/OR regional lymph node metastasis (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Modified Dukes stage B1 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pT3b: Tumor more than 5 cm in greatest dimension, limited to dermis and greater than 2 mm in thickness, but not more than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tumor ulceration absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
pN1a: Metastasis in 1 to 3 regional lymph nodes (esophagus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
T2a (IIA): Tumor of uterine cervix, T2 without parametrial invasion |
Interprets |
False |
Lesion observable |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |