Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
A rare dysostosis with predominant vertebral involvement characterized by paraspinal ligament ossification (most pronounced in the lower thoracic region), osteophytosis, marginal sacroiliac joint sclerosis, and punctate hyperkeratosis on the soles and palms. Patients may be asymptomatic or present mild to moderate back pain. There have been no further descriptions in the literature since 1969. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hyperkeratotic eczema of soles |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hyperkeratotic eczema of palms and soles (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Microwave ablation of verruca plantaris |
Procedure site - Direct (attribute) |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Structure of sweat gland bearing skin of sole of foot (body structure) |
Is a |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Pustular psoriasis of sole of foot (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Acropustulosis of infancy |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Pustular bacterid |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Frictional lichenoid eruption (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Pustular psoriasis of palms and soles (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Acrokerato-elastoidosis |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Keratoderma areata |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Mutilating keratoderma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Intractable plantar keratoma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Palmoplantar keratoderma transgrediens |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Autosomal dominant mutilating keratoderma |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Acroerythrokeratoderma |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Progressive palmoplantar keratoderma of Greither |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Epidermolytic palmoplantar keratoderma of Vorner |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A hereditary palmoplantar keratoderma with characteristics of the combination of bilateral mutilating transgredient palmoplantar keratoderma and periorificial keratotic plaques. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Keratoderma with pachyonychia congenita |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Palmoplantar hyperkeratosis sclerodactyly syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Papuloverrucous palmoplantar keratoderma of Jakac-Wolf |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hairy malformation of palms and soles |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hereditary palmoplantar keratoderma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Palmoplantar keratoderma with leukoplakia (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Papillon-Lefèvre syndrome |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Hereditary diffuse palmoplantar keratoderma |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Punctate palmoplantar keratoderma (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Palmoplantar hyperkeratosis-hyperpigmentation syndrome of Cantu (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Acquired keratoderma palmaris et plantaris |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Focal acral hyperkeratosis (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Plantar callosity (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Follicular atrophoderma with palmoplantar hyperkeratosis (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Hidrotic ectodermal dysplasia syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cole disease |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Palmoplantar keratoderma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Autosomal recessive palmoplantar keratoderma and congenital alopecia syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
A rare genetic skin disorder characterized by absence of scalp and body hair and palmoplantar keratoderma, without other hand complications. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
A rare genetic ectodermal dysplasia syndrome characterised by woolly hair (presenting at birth), palmoplantar keratoderma (developing in the first year of life) and dilated cardiomyopathy with predominant left ventricle involvement (developing in childhood) which can lead to life-threatening heart failure in childhood or adolescence. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Haim Munk syndrome |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
A rare dysostosis with predominant vertebral involvement characterized by paraspinal ligament ossification (most pronounced in the lower thoracic region), osteophytosis, marginal sacroiliac joint sclerosis, and punctate hyperkeratosis on the soles and palms. Patients may be asymptomatic or present mild to moderate back pain. There have been no further descriptions in the literature since 1969. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Diffuse palmoplantar keratoderma and acrocyanosis syndrome |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Palmoplantar keratoderma, 46,XX sex reversal, predisposition to squamous cell carcinoma syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Palmoplantar keratoderma with deafness syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
A rare autosomal recessive, isolated diffuse palmoplantar keratoderma characterized by transgressive and nonprogressive palmoplantar keratoderma resembling a mild form of mal de Meleda. |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Spastic paraplegia, intellectual disability, palmoplantar hyperkeratosis syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Cerebral dysgenesis, neuropathy, ichthyosis, palmoplantar keratoderma syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Palmoplantar keratoderma with clinodactyly syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Keratosis palmoplantaris and arrhythmogenic cardiomyopathy syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Autosomal dominant diffuse palmoplantar keratoderma Norrbotten type (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare hereditary skin disease characterized by irregularly distributed epidermal papular/punctate hyperkeratosis of the palms and soles with wide variation among patients. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hereditary palmoplantar keratoderma Gamborg Nielsen type (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Skin fragillity, woolly hair, palmoplantar keratoderma syndrome |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
Focal palmoplantar keratoderma with joint keratoses |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Diffuse palmoplantar keratoderma with painful fissures |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Leukoencephalopathy, palmoplantar keratoderma syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Hypotrichosis, osteolysis, periodontitis, palmoplantar keratoderma syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
7 |
Curly hair, acral keratoderma, caries syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
7 |
Keratosis linearis-ichthyosis congenita-sclerosing keratoderma syndrome is an inherited epidermal disorder characterised by palmoplantar keratoderma, linear hyperkeratotic papules on the flexural side of large joints (cord-like distribution around wrists, in antecubital and popliteal folds), hyperkeratotic plaques (on neck, axillae, elbows, wrists, and knees), mild ichthyosiform scaling, and sclerotic constrictions around fingers that present flexural deformities. |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Wooly hair with palmoplantar keratoderma syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Striate palmoplantar keratoderma |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Focal palmoplantar and gingival keratoderma (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Nail and tooth abnormalities, marginal palmoplantar keratoderma, oral hyperpigmentation syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
7 |
Punctate palmoplantar keratoderma type 2 is a type of isolated, punctate, hereditary palmoplantar keratoderma characterized by multiple, asymptomatic, 1 to 2 mm-long, firm, hyperkeratotic projections (spiny keratosis) on the palms, soles and digits (typically confined to their volar and/or lateral aspects). Histopathologically, compact columnar parakeratosis over hypo- or agranular epidermis is observed. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hypohidrosis, enamel hypoplasia, palmoplantar keratoderma, intellectual disability syndrome (disorder) |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Corneal intraepithelial dyskeratosis, palmoplantar hyperkeratosis, laryngeal dyskeratosis syndrome |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Palmoplantar keratoderma, spastic paralysis syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Keratoderma hereditarium mutilans with ichthyosis syndrome |
Finding site |
False |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Keratoderma hereditarium mutilans with ichthyosis syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
6 |
Acropustulosis of infancy |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Keratosis palmoplantaris and arrhythmogenic cardiomyopathy syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Acral erythema due to cytotoxic therapy (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Pustular bacterid |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Palmoplantar sarcoidosis (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Hyperkeratotic eczema of palms and soles (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Hyperkeratotic eczema of soles |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Paving stone nevus |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Focal palmoplantar and gingival keratoderma (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Striate palmoplantar keratoderma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Pachyonychia congenita syndrome |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Pachyonychia congenita type II of Jackson-Lawler |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Pachyonychia congenita type III of Schafer-Brunauer |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Aquagenic palmoplantar keratoderma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Palmoplantar keratoderma, hereditary motor and sensory neuropathy syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare genetic skin disease characterised by generalised skin peeling or superficial blisters without scarring, leukonychia, acral punctate keratoses coalescing into focal keratoderma on the weight-bearing areas, painful angular cheilitis, and knuckle pads with multiple hyperkeratotic micropapules. The skin appears dry and scaly with superficial exfoliation and underlying erythema. Histopathologic examination of affected skin areas is not specific and shows hyperkeratosis, acanthosis, and occasional intraepidermal clefting with irregular acantholysis. |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Punctate acrokeratoderma freckle-like pigmentation |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Drug-induced palmoplantar pustular psoriasis |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Metastatic plantar verrucous carcinoma |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Primary plantar verrucous carcinoma (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Isolated focal non-epidermolytic palmoplantar keratoderma (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Ectodermal dysplasia, hyperhidrosis, cutaneous syndactyly syndrome (disorder) |
Finding site |
True |
Skin structure of sole of foot (body structure) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |