Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Indinavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Saquinavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Nelfinavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Retroviral protease inhibitor |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir- and lamivudine- and zidovudine-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir sulfate 300mg tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir sulfate 20mg/mL solution |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ritonavir |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Amprenavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Lopinavir |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely abacavir 300 milligram and lamivudine 150 milligram and zidovudine 300 milligram/1 each conventional release oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir sulfate + lamivudine + zidovudine |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Atazanavir sulphate |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Fosamprenavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir 300mg tablet (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely abacavir (as abacavir sulfate) 20 milligram/1 milliliter conventional release oral solution (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir sulfate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Atazanavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir or abacavir derivative |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tipranavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Darunavir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Boceprevir (substance) |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Telaprevir |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Simeprevir (substance) |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cobicistat |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Allergy to protease inhibitor (finding) |
Causative agent (attribute) |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Steatosis of liver caused by retroviral protease inhibitor |
Causative agent (attribute) |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Asunaprevir (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing protease inhibitor (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Abacavir (substance) |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Abacavir sulfate (substance) |
Is a |
False |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Saquinavir mesilate |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Nelfinavir mesylate |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Indinavir sulfate |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Hepatitis C virus NS3/4A protease inhibitor |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Fosamprenavir calcium (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Darunavir ethanolate (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Darunavir propylene glycolate |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ecadotril (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with Severe acute respiratory syndrome coronavirus main protease inhibitor mechanism of action (substance) |
Is a |
True |
Protease inhibitor |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|