372536007: Topotecan (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Topoisomerase inhibitor\Topotecan (substance)

\Drug or medicament (substance)\Antineoplastic agent (substance)\Topotecan (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Alkaloid (substance)\Topotecan (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Topotecan (substance)	Is a	Topoisomerase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Is a	classe d'allergènes	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Has disposition	Topoisomerase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan (substance)	Is a	Alkaloid (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Topotecan hydrochloride	Is a	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing topotecan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for injection (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan 1mg powder for infusion solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for injection (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Topotecan-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing topotecan in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
chlorhydrate de topotécan	Is a	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has basis of strength substance (attribute)	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has basis of strength substance (attribute)	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan 250 microgram/1 each conventional release oral capsule	Has precise active ingredient	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan 1 milligram/1 each conventional release oral capsule	Has precise active ingredient	False	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topotecan hydrochloride	Is modification of (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing only topotecan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topotecan only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only topotecan in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely topotecan (as topotecan hydrochloride) 250 microgram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for infusion vial	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for infusion and/or injection vial	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for infusion and/or injection vial	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for infusion vial	Has basis of strength substance (attribute)	True	Topotecan (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1197829012	Topotecan (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211069010	Topotecan	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1197829012	Topotecan (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1197829012	Topotecan (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211069010	Topotecan	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1211069010	Topotecan	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
56031000195119	topotecan	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71141000195118	Topotecan	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846861000172112	topotécane	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
1119651000241112	topotécan	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846861000172112	topotécane	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
1119651000241112	topotécan	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
56031000195119	topotecan	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71141000195118	Topotecan	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module