372567009: Metformin (substance)

SNOMED CT Concept\Substance\...

\Drug or medicament (substance)\Biguanide oral hypoglycemic agent (substance)\Metformin (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Biguanide\Biguanide oral hypoglycemic agent (substance)\Metformin (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Metformin (substance)	Is a	Biguanide	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Metformin (substance)	Is a	Biguanide oral hypoglycemic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Metformin hydrochloride	Is a	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Poisoning by metformin	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental poisoning by metformin	Causative agent (attribute)	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Intentional poisoning by metformin	Causative agent (attribute)	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Poisoning caused by metformin of undetermined intent	Causative agent (attribute)	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin adverse reaction	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Allergy to metformin (finding)	Causative agent (attribute)	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Overdose of metformin	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental overdose by metformin (disorder)	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Intentional overdose by metformin	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
surdose de metformine d'intention indéterminée	Causative agent (attribute)	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and rosiglitazone-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely metformin hydrochloride 500 milligram and rosiglitazone (as rosiglitazone maleate) 1 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Metformin hydrochloride 500 mg and rosiglitazone (as rosiglitazone maleate) 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely metformin hydrochloride 500 milligram and rosiglitazone maleate 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely metformin hydrochloride 1 gram and rosiglitazone (as rosiglitazone maleate) 2 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely metformin hydrochloride 1 gram and rosiglitazone (as rosiglitazone maleate) 4 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Accidental poisoning by metformin	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Intentional poisoning by metformin	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing metformin and pioglitazone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely metformin hydrochloride 500 milligram and pioglitazone hydrochloride 15 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Metformin hydrochloride 850 mg and pioglitazone (as pioglitazone hydrochloride) 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing metformin and sitagliptin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metformin and repaglinide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Pioglitazone 30mg + metformin 1g m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Pioglitazone 15mg + metformin 1g m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to metformin (finding)	Causative agent (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Empagliflozin- and metformin-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing canagliflozin and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Canagliflozin- and metformin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Linagliptin- and metformin-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing linagliptin and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin pamoate (substance)	Is a	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Metformin hydrochloride	Is modification of (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Metformin pamoate (substance)	Is modification of (attribute)	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Pioglitazone 30mg + metformin 1g prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Pioglitazone 15mg + metformin 1g prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing metformin and rosiglitazone in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and pioglitazone-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing glibenclamide and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Glibenclamide- and metformin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing glipizide and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Glipizide- and metformin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metformin and repaglinide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and sitagliptin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only canagliflozin and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only empagliflozin and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only glibenclamide and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Glipizide and metformin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin and repaglinide only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and rosiglitazone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin and pioglitazone only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and sitagliptin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Linagliptin and metformin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only glibenclamide and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Linagliptin and metformin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Canagliflozin and metformin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only glipizide and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and pioglitazone in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and repaglinide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin and rosiglitazone only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and sitagliptin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metformin and saxagliptin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and saxagliptin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin and saxagliptin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin and saxagliptin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dapagliflozin- and metformin- and saxagliptin-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dapagliflozin and metformin and saxagliptin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only dapagliflozin and metformin and saxagliptin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dapagliflozin- and metformin- and saxagliptin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and vildagliptin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and vildagliptin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metformin and vildagliptin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and vildagliptin-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing gliclazide and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only gliclazide and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing gliclazide and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only gliclazide and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing alogliptin and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Alogliptin and metformin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing alogliptin and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Alogliptin and metformin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin- and voglibose-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only metformin and voglibose (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing metformin and voglibose in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Metformin and voglibose only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only empagliflozin and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing dapagliflozin and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing dapagliflozin and metformin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only dapagliflozin and metformin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dapagliflozin and metformin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metformin therapy (procedure)	Direct substance	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Empagliflozin- and metformin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metformin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1197861011	Metformin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211097016	Metformin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1197861011	Metformin (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1197861011	Metformin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211097016	Metformin	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1211097016	Metformin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
51911000195119	metformina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
67041000195116	Metformin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
824311000172110	metformine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
824311000172110	metformine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
51911000195119	metformina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
67041000195116	Metformin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module