| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| Betahistidine (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Benzoquinonium |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Chlorisondamine |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Pentolinium |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Mebutamate |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Trimethidinium (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hexamethonium |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Tienilic acid |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Pentamethonium bromide |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Protoveratrine A |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Cryptenamine (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Angiotensin-converting enzyme inhibitor |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Centrally acting hypotensive agent |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Vasodilator (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Mecamylamine (substance) |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Nitroprusside (substance) |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Rauwolfia alkaloid (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Substance with angiotensin II receptor antagonist mechanism of action (substance) |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Pargyline |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Trimetaphan |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| médicament antihypertenseur |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adrenergic neurone blocking drug poisoning |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Amiloride and loop diuretic adverse reaction |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antihypertensive adverse reaction |
Causative agent (attribute) |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Adrenergic neurone blocking drug adverse reaction |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Ganglion-blocking drug adverse reaction |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Trimetaphan adverse reaction (disorder) |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Amiloride and loop diuretic allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antihypertensive allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adrenergic neurone blocking drug allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Ganglion-blocking drug allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Allergy to trimethaphan |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antihypertensive overdose |
Causative agent (attribute) |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Adrenergic neurone blocking drug overdose (disorder) |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Accidental antihypertensive overdose (disorder) |
Causative agent (attribute) |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Intentional antihypertensive overdose |
Causative agent (attribute) |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Antihypertensive overdose of undetermined intent |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| fœtus ou nouveau-né affecté par l'usage maternel de médicament antihypertenseur |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Calcium-channel blocker+angiotensin-converting enzyme inhibitor (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing felodipine and ramipril (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely felodipine 2.5 milligram and ramipril 2.5 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Felodipine 5 mg and ramipril 5 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Centrally acting antihypertensive drug |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adrenergic neurone blocker-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing bethanidine sulfate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely betanidine 10 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing ganglion blocker (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Trimetaphan camsylate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Trimetaphan camsylate 250mg/5mL infusion concentrate (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Other antihypertensives |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antihypertensives+barbiturates |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Betanidine-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing trimetaphan (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Angiotensin II receptor antagonist+diuretic |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| olmésartan médoxomil |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Olmesartan-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Olmesartan medoxomil 5 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Olmesartan medoxomil 20 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Olmesartan medoxomil 40 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Deserpidine (substance) |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Guanethidine (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Metirosine |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Bethanidine sulfate |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Imidazoline receptor agonist |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Debrisoquine (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing angiotensin-converting enzyme inhibitor (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Angiotensin II receptor antagonist (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Eplerenone-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to reserpine |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to other antihypertensives |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to antihypertensives NOS |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Eplerenone 25 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Eplerenone 50 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Inspra 50mg tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Inspra 25mg tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Eplerenone 100 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Inspra 100mg tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Angiotensin II receptor antagonist adverse reaction (disorder) |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hydrochlorothiazide 12.5 mg and telmisartan 40 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hydrochlorothiazide 12.5 mg and telmisartan 80 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely olmesartan medoxomil 10 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Eplerenone |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to ganglion blocking drug |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to pentamethonium bromide |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to trimetaphan camsylate (finding) |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to ganglion blockers NOS |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Substance with beta adrenergic receptor antagonist mechanism of action (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Fetal captopril/enalapril syndrome |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
| Ganglion blocking agent |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Betanidine |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Ivabradine |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Poisoning caused by antihypertensive agent |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Adrenergic neurone blocking drug poisoning |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| [X]Poisoning by other antihypertensive drugs, not elsewhere classified |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Renin inhibitor |
Is a |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Ketanserin |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antihypertensive allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Adrenergic neurone blocking drug allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Losartan allergy |
Causative agent (attribute) |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Renin inhibitor-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Substance with endothelin receptor antagonist mechanism of action (substance) |
Is a |
True |
Hypotensive agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
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