372726002: Amitriptyline (substance)

SNOMED CT Concept\Substance\...

\Drug or medicament (substance)\Central nervous system agent (substance)\Psychoactive substance\Psychotropic agent (substance)\Antidepressant (substance)\Tricyclic antidepressant (substance)\Amitriptyline (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\...

\Organic cyclic compound\Tricyclic compound (substance)\Tricyclic antidepressant (substance)\Amitriptyline (substance)

\Hydrocarbon\Aromatic hydrocarbon\Benzocycloheptene (substance)\Dibenzocycloheptene\Amitriptyline (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Amitriptyline (substance)	Is a	Tricyclic antidepressant (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline (substance)	Is a	Dibenzocycloheptene	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Amitriptyline hydrochloride	Is a	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline and nortriptyline measurement (procedure)	Component	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Accidental amitriptyline poisoning	Causative agent (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Intentional amitriptyline poisoning	Causative agent (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
intoxication par l'amitriptyline d'intention indéterminée	Causative agent (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline adverse reaction	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Allergy to amitriptyline (finding)	Causative agent (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline overdose	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental amitriptyline overdose	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Intentional amitriptyline overdose	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
surdose d'amitriptyline d'intention indéterminée	Causative agent (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline 25mg/5mL s/f oral solution (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline 50mg/5mL s/f oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline hydrochloride 12.5 milligram and chlordiazepoxide 5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline hydrochloride + perphenazine 10mg/2mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 10 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline hydrochloride + perphenazine 25mg/2mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline hydrochloride + perphenazine 25mg/4mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline hydrochloride + perphenazine 50mg/4mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing amitriptyline in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Oral form amitriptyline m/r	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Parenteral amitriptyline (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Serum nortriptyline level (procedure)	Component	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing amitriptyline (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline measurement	Component	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Poisoning by amitriptyline	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline hydrochloride+perphenazine 25mg/2mg tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 10 milligram and perphenazine 2 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 25 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 50 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline hydrochloride + perphenazine	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Intentional amitriptyline poisoning	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental poisoning by amitriptyline	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline hydrochloride+perphenazine 25mg/2mg tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 10 milligram and perphenazine 2 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 10 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 25 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely amitriptyline 50 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing amitriptyline and perphenazine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Allergy to amitriptyline (finding)	Causative agent (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Serum amitriptyline level (procedure)	Component	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Amitriptyline hydrochloride+perphenazine 25mg/2mg tablet (substance)	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 10 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely amitriptyline 25 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely amitriptyline 50 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 50 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 10 milligram and perphenazine 2 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely amitriptyline 10 milligram and perphenazine 2 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Amitriptyline hydrochloride+perphenazine 25mg/2mg tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Amitriptyline hydrochloride+perphenazine 25mg/2mg tablet (substance)	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely amitriptyline 10 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 10 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 25 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 25 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline hydrochloride	Is modification of (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Amitriptyline hydrochloride+perphenazine 25mg/2mg tablet (substance)	Has precise active ingredient	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 10 milligram and perphenazine 2 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely amitriptyline 10 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Amitriptyline- and chlordiazepoxide-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing amitriptyline and chlordiazepoxide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline- and perphenazine-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline 25 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely amitriptyline 50 milligram and perphenazine 4 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only amitriptyline (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only amitriptyline and chlordiazepoxide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline and perphenazine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only amitriptyline and chlordiazepoxide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only amitriptyline and perphenazine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only amitriptyline in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline (as amitriptyline hydrochloride) 25 mg and chlordiazepoxide 10 mg oral tablet	Has basis of strength substance (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely amitriptyline (as amitriptyline hydrochloride) 12.5 milligram and chlordiazepoxide 5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline (as amitriptyline hydrochloride) 12.5 mg and chlordiazepoxide 10 mg oral tablet	Has basis of strength substance (attribute)	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amitriptyline and nortriptyline measurement (procedure)	Component	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Serum amitriptyline level (procedure)	Component	True	Amitriptyline (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1198021014	Amitriptyline (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211249012	Amitriptyline	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1198021014	Amitriptyline (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1198021014	Amitriptyline (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211249012	Amitriptyline	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1211249012	Amitriptyline	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
54731000195113	amitriptilina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69111000195111	Amitriptylin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
791051000172115	amitriptyline	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
791051000172115	amitriptyline	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
54731000195113	amitriptilina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69111000195111	Amitriptylin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module