| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| Dezocine 15mg/mL injection solution 1mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| agent antidémence |
Is a |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Substance with glutamate receptor antagonist mechanism of action (substance) |
Is a |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Substance with potassium channel blocker mechanism of action (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely pergolide 1 milligram/1 each conventional release oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hydrocodone polistirex 20mg/chlorpheniremine polistirex 4mg per 5mL oral m/r suspension |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Oxycodone-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing oxycodone terephthalate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely oxycodone hydrochloride 7.5 milligram and paracetamol 325 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Oxycodone hydrochloride 10 mg and paracetamol 325 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Oxycodone hydrochloride 10 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Oxycodone hydrochloride 7.5 mg and paracetamol 500 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Oxycodone hydrochloride 10 mg and paracetamol 650 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Dextropropoxyphene napsylate 100 mg and paracetamol 500 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing hydromorphone (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hydromorphone hydrochloride 12mg m/r capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hydromorphone hydrochloride 32mg m/r capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing ibuprofen and oxycodone (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Ibuprofen 400 mg and oxycodone 5 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Codeine phosphate 12.5 mg and ibuprofen 200 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Codeine phosphate 12.8 mg and ibuprofen 200 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Ibuprofen+codeine phosphate 300mg/20mg m/r tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Ibuprofen+codeine phosphate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Fentanyl 12 microgram/hour prolonged-release transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing phenacemide (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Psychotropic agent (substance) |
Is a |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| GABA receptor antagonist |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| [X]Benzodiazepines causing adverse effects in therapeutic use |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| [X]Drugs primarily affecting the central nervous system causing adverse effects in therapeutic use |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Alcohol deterrent overdose |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antabuse overdose |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Accidental antabuse overdose |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Intentional antabuse overdose |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Antabuse overdose of undetermined intent |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Disulfiram 200 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Acamprosate calcium (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Acamprosate calcium 333mg e/c tablet (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing disulfiram (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Accidental poisoning caused by intravenous anesthetics |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Accidental poisoning caused by central nervous system drug |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Adverse reaction to central nervous system muscle-tone depressants NOS |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to central nervous system depressants and anesthetics NOS |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Disulfiram 250 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely disulfiram 500 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing acamprosate (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Psychoactive substance |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Idebenone (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Sodium phenylbutyrate (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Thiethylperazine (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Tetrabenazine |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Thalidomide poisoning |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Adverse reaction to other central nervous system depressants and anesthetics |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Drug groups primarily affecting the central nervous system allergy |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Tafamidis |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| NMDA receptor antagonist |
Is a |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Monoamine oxidase inhibitor |
Is a |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Thiethylperazine malate |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Thiethylperazine maleate |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Tafamidis meglumine (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Accidental narcotic poisoning |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Intentional narcotic poisoning |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Narcotic poisoning of undetermined intent |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Poisoning caused by opiate AND/OR related narcotic |
Causative agent (attribute) |
False |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Dihydroergocornine mesilate (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Dihydroergocristine mesilate |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Rivastigmine tartrate |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Tacrine hydrochloride |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Tacrine |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Donepezil (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Donepezil hydrochloride (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Galantamine (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Rivastigmine |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Memantine hydrochloride (substance) |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Donepezil hydrochloride monohydrate |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Parkinsonism caused by dopamine depleting agent (disorder) |
Causative agent (attribute) |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Ifenprodil |
Is a |
True |
Central nervous system agent (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
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