Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Chlorphenoxamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Desmethylastemizole |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Clemizole |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thenylpyramine |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tripelennamine citrate |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thenyldiamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Pyrathiazine (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thonzylamine |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Piperidine derivative |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Olopatadine (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ketotifen (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thiethylperazine (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phthalazinone derivative (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with histamine H1 receptor antagonist mechanism of action (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Propylamine derivative antihistamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethylenediamine derivative with histamine receptor antagonist mechanism of action (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Non-sedating antihistamine |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Sedating antihistamine |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thonzylamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethanolamine oleate (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Topical form antihistamine |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethanolamine oleate 5% injection (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing trimethobenzamide (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing ethanolamine derivative and histamine receptor antagonist (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Histamine receptor antagonist-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing piperazine derivative and histamine receptor antagonist (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethanolamine oleate 50mg/mL injection 2mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochloride 250 mg capsule (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely trimethobenzamide hydrochloride 100 milligram/1 each conventional release oral capsule (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochloride 100 mg/2% suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochloride 200 mg/2% suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochloride 100 mg/mL intramuscular solution(substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochlor 100mg/mL injection (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochlor 200mg |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochlor 100mg |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trimethobenzamide hydrochloride 100mg/mL bar |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Benzocaine + trimethobenzamide hydrochlor 2%ww/100mg suppositories |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Benzocaine 20 microgram and trimethobenzamide hydrochloride 200 mg rectal suppository |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing benzocaine and trimethobenzamide hydrochloride |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethanolamine oleate 5% injection solution 2 mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethanolamine oleate 5% injection solution 5 mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Poisoning by diphenylpyraline |
Causative agent (attribute) |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Poisoning by antihistamine |
Causative agent (attribute) |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Trimethobenzamide hydrochloride 300 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing trimethobenzamide hydrochloride |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing thiethylperazine (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thiethylperazine maleate 5mg/mL injection solution 2mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thiethylperazine malate 10 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing thiethylperazine in oral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing thiethylperazine in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Piperidine derivative-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Topical antihistamine adverse reaction |
Causative agent (attribute) |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Topical antihistamine allergy |
Causative agent (attribute) |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Adverse reaction to antihistamines |
Causative agent (attribute) |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Other antihistamine poisoning |
Causative agent (attribute) |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Screening for antihistamine in urine (procedure) |
Component |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Antihistamine measurement |
Component |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Topical antihistamine allergy |
Causative agent (attribute) |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Niaprazine (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Histamine H2 receptor antagonist |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Antihistamine prophylaxis (procedure) |
Direct substance |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Histamine H3 receptor antagonist |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ranitidine bismuth citrate (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Pizotifen (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Dimenhydrinate (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alimemazine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alimemazine tartrate |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
malate de pizotifène |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Piperazine derivative antihistamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Isothipendyl hydrochloride (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Azatadine maleate |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Piperidine derivative with histamine receptor antagonist mechanism of action (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cyproheptadine hydrochloride |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Promethazine hydrochloride |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Promethazine theoclate |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Azatadine (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Oxatomide (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Mebhydrolin (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phenindamine (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Doxylamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Chlorcyclizine |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ethanolamine derivative antihistamine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cyclizine lactate |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Isothipendyl |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cyclizine tartrate (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buclizine (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buclizine hydrochloride |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Promethazine (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Mequitazine |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cyclizine hydrochloride (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cyproheptadine (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cyclizine (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Chloropyrilene (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Olopatadine hydrochloride |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Doxylamine succinate |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phenindamine tartrate (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Captodiamine (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Captodiame hydrochloride (substance) |
Is a |
True |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Esomeprazole sodium (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Esomeprazole magnesium trihydrate (substance) |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Esomeprazole |
Is a |
False |
Histamine receptor antagonist |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|