372826007: Metoprolol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with adrenergic receptor antagonist mechanism of action\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Substance with beta-1 adrenergic receptor antagonist mechanism of action (substance)\Metoprolol

\Drug or medicament (substance)\Autonomic agent (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Substance with beta-1 adrenergic receptor antagonist mechanism of action (substance)\Metoprolol
\Drug or medicament (substance)\agent cardiovasculaire\Hypotensive agent (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Substance with beta-1 adrenergic receptor antagonist mechanism of action (substance)\Metoprolol

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amine and/or amine derivative\Amine\Amino alcohol (substance)\Alkanolamine (substance)\Propanolamine (substance)\Metoprolol

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Metoprolol	Is a	Substance with beta-1 adrenergic receptor antagonist mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol	Is a	Propanolamine (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol	Has disposition	Beta-1 adrenergic receptor antagonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol	Is a	Substance with beta adrenergic receptor antagonist mechanism of action (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Metoprolol tartrate (substance)	Is a	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol measurement	Component	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metoprolol adverse reaction	Causative agent (attribute)	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Hydrochlorothiazide 12.5 mg and metoprolol tartrate 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol tartrate+hydrochlorothiazide 200mg/25mg m/r tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol fumarate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol+diuretic	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol succinate 25mg tablet (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol succinate 50mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol succinate 100mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol succinate 200mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metoprolol in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing hydrochlorothiazide and metoprolol tartrate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol succinate (substance)	Is a	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely metoprolol tartrate 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing hydrochlorothiazide and metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely hydrochlorothiazide 25 milligram and metoprolol tartrate 50 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely hydrochlorothiazide 25 milligram and metoprolol tartrate 100 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely hydrochlorothiazide 50 milligram and metoprolol tartrate 100 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to metoprolol (finding)	Causative agent (attribute)	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely hydrochlorothiazide 12.5 milligram and metoprolol tartrate 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely hydrochlorothiazide 12.5 milligram and metoprolol tartrate 50 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to metoprolol (finding)	Causative agent (attribute)	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metoprolol tartrate (substance)	Is modification of (attribute)	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Metoprolol succinate (substance)	Is modification of (attribute)	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Hydrochlorothiazide- and metoprolol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only hydrochlorothiazide and metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metoprolol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only hydrochlorothiazide and metoprolol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metoprolol only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metoprolol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only metoprolol and telmisartan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metoprolol and telmisartan in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Metoprolol and telmisartan only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing metoprolol and telmisartan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing amlodipine and metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only amlodipine and metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amlodipine- and metoprolol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Amlodipine and metoprolol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
(S)-metoprolol succinate (substance)	Is modification of (attribute)	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
(S)-metoprolol tartrate (substance)	Is modification of (attribute)	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing levamlodipine and metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only levamlodipine and metoprolol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing levamlodipine and metoprolol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only levamlodipine and metoprolol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Metoprolol	Inferred relationship	Existential restriction modifier (core metadata concept)	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1198121011	Metoprolol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211346015	Metoprolol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1198121011	Metoprolol (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1198121011	Metoprolol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1211346015	Metoprolol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1211346015	Metoprolol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
58341000195112	metoprololo	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
73431000195117	Metoprolol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
825311000172111	métoprolol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
825311000172111	métoprolol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
58341000195112	metoprololo	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
73431000195117	Metoprolol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module