| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| Timolol maleate (substance) |
Is a |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol measurement |
Component |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol adverse reaction |
Causative agent (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Allergy to timolol (finding) |
Causative agent (attribute) |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.25% liquid eye gel (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.5% liquid eye gel |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol (as timolol maleate) 2.5 mg/mL eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Dorzolamide- and timolol-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Dorzolamide (as dorzolamide hydrochloride) 20 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol maleate+diuretic |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Oral timolol (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Topical timolol (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.25% ophthalmic solution |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.5% solution (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Hydrochlorothiazide + timolol maleate 25mg/10mg tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Latanoprost- and timolol-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Latanoprost+timolol 0.005%/0.5% eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.1% liquid eye gel |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol maleate+bendroflumethiazide |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol maleate+co-amilozide (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.5% eye drops preservative free |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol (as timolol maleate) 2.5 mg/mL eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.25% metered dose eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol 0.1% liquid eye gel |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing precisely latanoprost 50 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol maleate 0.5% gel forming ophthalmic solution |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Timolol maleate 0.25% gel forming ophthalmic solution |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing brimonidine and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Brimonidine 0.2%/timolol 0.5% eye drops |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing bendroflumethiazide and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing timolol in ophthalmic dosage form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing timolol and travoprost (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Product containing bimatoprost and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Allergy to timolol (finding) |
Causative agent (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol maleate (substance) |
Is modification of (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
| Product containing bendroflumethiazide and timolol in oral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing amiloride and hydrochlorothiazide and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Amiloride- and hydrochlorothiazide- and timolol-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol (as timolol maleate) 1 mg/mL eye gel |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol (as timolol maleate) 2.5 mg/mL eye gel |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol (as timolol maleate) 5 mg/mL eye gel |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol (as timolol maleate) 2.5 mg/mL eye drops |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing precisely latanoprost 50 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug) |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug) |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Dorzolamide (as dorzolamide hydrochloride) 20 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol-containing product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Hydrochlorothiazide- and timolol-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Latanoprost- and timolol-containing product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Dorzolamide- and timolol-containing product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing hydrochlorothiazide and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Bimatoprost and timolol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Amiloride and hydrochlorothiazide and timolol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Brimonidine and timolol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Product containing only bendroflumethiazide and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only dorzolamide and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only hydrochlorothiazide and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only timolol and travoprost (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Timolol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Latanoprost and timolol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Dorzolamide and timolol only product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Latanoprost and timolol only product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Hydrochlorothiazide and timolol only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only timolol in ocular dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only bendroflumethiazide and timolol in oral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Amiloride and hydrochlorothiazide and timolol only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing precisely timolol (as timolol maleate) 2.5 milligram/1 milliliter conventional release eye solution (clinical drug) |
Has basis of strength substance (attribute) |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye solution (clinical drug) |
Has basis of strength substance (attribute) |
False |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing brimonidine and timolol in ocular dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Brimonidine and timolol only product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Product containing precisely brimonidine tartrate 2 milligram/1 milliliter and timolol 5 milligram/1 milliliter conventional release eye solution (clinical drug) |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing precisely brimonidine tartrate 2 milligram/1 milliliter and timolol 5 milligram/1 milliliter conventional release eye solution (clinical drug) |
Has precise active ingredient |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Timolol and travoprost only product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Timolol- and travoprost-containing product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Timolol (as timolol maleate) 5 mg/mL and travoprost 40 microgram/mL eye drops |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Bimatoprost- and timolol-containing product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Bimatoprost and timolol only product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Product containing precisely bimatoprost 300 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug) |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
| Brinzolamide- and timolol-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing brinzolamide and timolol in ocular dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Brinzolamide and timolol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only brinzolamide and timolol in ocular dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Brinzolamide 10 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops suspension |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing precisely tafluprost 15 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release solution for eye drops (clinical drug) |
Has basis of strength substance (attribute) |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing tafluprost and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only tafluprost and timolol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Tafluprost- and timolol-containing product in ocular dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
| Product containing only tafluprost and timolol in ocular dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Timolol (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
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