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372917005: Substance with protein-tyrosine kinase inhibitor mechanism of action (substance)

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
1211435017 Protein-tyrosine kinase inhibitor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
3520810019 Substance with protein-tyrosine kinase inhibitor mechanism of action (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
3559306016 Substance with protein-tyrosine kinase inhibitor mechanism of action en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
1198212015 Protein-tyrosine kinase inhibitor (substance) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core
1198212015 Protein-tyrosine kinase inhibitor (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
1211435017 Protein-tyrosine kinase inhibitor en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
1211435017 Protein-tyrosine kinase inhibitor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
3520810019 Substance with protein-tyrosine kinase inhibitor mechanism of action (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
3559306016 Substance with protein-tyrosine kinase inhibitor mechanism of action en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

106 descendants. Search Descendants:

Expanded Value Set

Outbound Relationships Type Target Active Characteristic Refinability Group Values
Protein-tyrosine kinase inhibitor Is a Antineoplastic agent (substance) false Inferred relationship Existential restriction modifier (core metadata concept)
Protein-tyrosine kinase inhibitor Is a Epidermal growth factor receptor antagonist false Inferred relationship Existential restriction modifier (core metadata concept)
Protein-tyrosine kinase inhibitor Is a Protein kinase inhibitor true Inferred relationship Existential restriction modifier (core metadata concept)
Protein-tyrosine kinase inhibitor Has disposition Protein-tyrosine kinase inhibitor (disposition) true Inferred relationship Existential restriction modifier (core metadata concept)
Inbound Relationships Type Active Source Characteristic Refinability Group
Imatinib mesilate Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Protein-tyrosine kinase inhibitor-containing product The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept) 1
Product containing imatinib (medicinal product) The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Product containing gefitinib (medicinal product) The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Gefitinib 250 mg oral tablet The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Iressa 250mg tablet The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Product containing precisely imatinib 100 milligram/1 each conventional release oral capsule The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Gefitinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Product containing precisely imatinib 400 milligram/1 each conventional release oral tablet The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Imatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Erlotinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Vandetanib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Sunitinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Sorafenib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Dasatinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lapatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Nilotinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Axitinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Pazopanib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Toceranib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Regorafenib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Ruxolitinib Is a False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Bosutinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Ceritinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Afatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Crizotinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Ponatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Epidermal growth factor receptor antagonist Is a False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Janus kinase inhibitor Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Substance with non-specific protein-tyrosine kinase inhibitor mechanism of action (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lenvatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Cobimetinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Alectinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Cabozantinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Midostaurin Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tivozanib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Neratinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Brigatinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Erlotinib hydrochloride (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Nilotinib hydrochloride monohydrate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Ponatinib hydrochloride (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Sunitinib malate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Sorafenib tosylate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Toceranib phosphate Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Afatinib dimaleate Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Bosutinib monohydrate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Pazopanib hydrochloride (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Cobimetinib fumarate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Fostamatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lenvatinib mesilate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Neratinib maleate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Rho-associated protein kinase inhibitor Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Dacomitinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Alectinib hydrochloride Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Gilteritinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lorlatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Larotrectinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Nilotinib hydrochloride (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lapatinib ditosylate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lapatinib ditosylate monohydrate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Human epidermal growth factor receptor 2 inhibitor Is a False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Erdafitinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Pexidartinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Entrectinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Cabozantinib s-malate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tucatinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Pemigatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Capmatinib Is a False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Selpercatinib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Ripretinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Pralsetinib (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tirbanibulin Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tepotinib Is a False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tepotinib hydrochloride Is a False Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Dacomitinib monohydrate Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Mesenchymal epithelial transition inhibitor Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tivozanib hydrochloride Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tivozanib hydrochloride monohydrate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Gilteritinib fumarate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Larotrectinib sulfate Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Dasatinib monohydrate (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Dacomitinib anhydrous (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Dasatinib anhydrous Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Tivozanib hydrochloride anhydrous (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Nilotinib hydrochloride anhydrous (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Lapatinib ditosylate anhydrous (substance) Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Asciminib hydrochloride Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Fostamatinib disodium hexahydrate Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)
Asciminib Is a True Protein-tyrosine kinase inhibitor Inferred relationship Existential restriction modifier (core metadata concept)

This concept is not in any reference sets

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