Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Denileukin diftitox (substance) |
Is a |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing temozolomide (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cytotoxic cerebral edema |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Chemotherapy sickness |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Post-chemotherapy testicular hypofunction |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cytotoxic drug-induced hypospermatogenesis |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Congenital malformation caused by cytotoxic agents (disorder) |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cytotoxic superficial application |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely temozolomide 5 milligram/1 each conventional release oral capsule (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely temozolomide 20 milligram/1 each conventional release oral capsule (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely temozolomide 100 milligram/1 each conventional release oral capsule (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Temozolomide 250 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Fetal aminopterin syndrome |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
médicament cytotoxique |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Temozolomide (substance) |
Is a |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Altretamine |
Is a |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cytotoxic drug therapy NOS |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Synthetic cytotoxic triazine derivative |
Is a |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Recombinant interleukin 2 moiety |
Is a |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Introduction of cytotoxic substance into pleural cavity |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Intraperitoneal administration of cytotoxic drug |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Injection of cytotoxic substance into artery of head (procedure) |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cytotoxic given orally |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cytotoxic superficial application |
Direct substance |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Intraperitoneal administration of cytotoxic drug |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cytotoxic given orally |
Direct substance |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Injection of cytotoxic substance into artery of head (procedure) |
Direct substance |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Intraperitoneal administration of cytotoxic drug |
Direct substance |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Introduction of cytotoxic substance into pleural cavity |
Direct substance |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Dermatosis due to cytotoxic therapy |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Syringosquamous metaplasia due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cutaneous inflammation due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Stomatitis due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Acral erythema due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Pseudoscleroderma due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Methotrexate skin ulceration (disorder) |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cutaneous ulceration due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Nail dystrophy due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
False |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Ultraviolet recall reaction due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Radiation recall reaction due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Administration of cytotoxic agent via oral route |
Direct substance |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cytotoxic drug-induced hypospermatogenesis |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cutaneous ulceration due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Stomatitis due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Acral erythema due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Cytotoxic cerebral edema |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Recombinant interleukin 2 |
Is a |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Congenital malformation caused by cytotoxic agents (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
5 |
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder) |
Causative agent (attribute) |
True |
Cytotoxic (substance) |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |