385556006: Tenofovir disoproxil fumarate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Reverse transcriptase inhibitor\Tenofovir disoproxil fumarate (substance)
\Substance categorized by disposition\Substance with antiviral mechanism of action (substance)\Substance with antiretroviral mechanism of action (substance)\Reverse transcriptase inhibitor\Tenofovir disoproxil fumarate (substance)

\Drug or medicament (substance)\Anti-infective agent (substance)\Substance with antiviral mechanism of action (substance)\Substance with antiretroviral mechanism of action (substance)\Reverse transcriptase inhibitor\Tenofovir disoproxil fumarate (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\...

\Organic acid and/or organic acid derivative (substance)\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic ester (substance)\Tenofovir disoproxil fumarate (substance)

\Ester\Carboxylic ester (substance)\Tenofovir disoproxil fumarate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tenofovir disoproxil fumarate (substance)	Is a	Reverse transcriptase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil fumarate (substance)	Is a	Tenofovir (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil fumarate (substance)	Is a	Tenofovir disoproxil (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil fumarate (substance)	Has disposition	Reverse transcriptase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil fumarate (substance)	Is a	Transferase inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil fumarate (substance)	Is a	Carboxylic ester (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil fumarate (substance)	Is modification of (attribute)	Tenofovir disoproxil (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tenofovir 300mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil 245mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tenofovir disoproxil 245mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing emtricitabine and tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing efavirenz and emtricitabine and tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	Has basis of strength substance (attribute)	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Efavirenz 600 mg and emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg oral tablet	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely emtricitabine 200 milligram and tenofovir disoproxil fumarate 136 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely efavirenz 600 milligram and lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely efavirenz 600 milligram and lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tenofovir disoproxil fumarate 150 mg oral tablet	Has basis of strength substance (attribute)	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tenofovir disoproxil fumarate 150 mg oral tablet	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely dolutegravir (as dolutegravir sodium) 50 milligram and lamivudine 300 milligram and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Efavirenz 400 mg and lamivudine 300 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Emtricitabine 200 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely lamivudine 300 milligram and tenofovir disoproxil fumarate 300 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Doravirine 100 mg and lamivudine 300 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Emtricitabine 200 mg and rilpivirine (as rilpivirine hydrochloride) 25 mg and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 mg oral tablet	Has precise active ingredient	True	Tenofovir disoproxil fumarate (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1459735016	Tenofovir disoproxil fumarate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1479761018	Tenofovir disoproxil fumarate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1459735016	Tenofovir disoproxil fumarate (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1459735016	Tenofovir disoproxil fumarate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1479761018	Tenofovir disoproxil fumarate	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1479761018	Tenofovir disoproxil fumarate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
30261000188112	ténofovir disoproxil fumarate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
844251000172117	fumarate de ténofovir disoproxil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
30261000188112	ténofovir disoproxil fumarate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
844251000172117	fumarate de ténofovir disoproxil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module