386856007: Donepezil hydrochloride (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Acetylcholinesterase inhibitor\Substance with centrally acting acetylcholinesterase inhibitor mechanism of action (substance)\Donepezil hydrochloride (substance)
\Substance categorized by disposition\Receptor agonist\Substance with sigma-1 receptor agonist mechanism of action (substance)\Donepezil hydrochloride (substance)

\Drug or medicament (substance)\Autonomic agent (substance)\Parasympathomimetic agent (substance)\Acetylcholinesterase inhibitor\Substance with centrally acting acetylcholinesterase inhibitor mechanism of action (substance)\Donepezil hydrochloride (substance)
\Drug or medicament (substance)\Central nervous system agent (substance)\Donepezil hydrochloride (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative\Donepezil hydrochloride (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative\Donepezil hydrochloride (substance)
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Piperidine derivative\Donepezil hydrochloride (substance)
\Organic compound\Ketone\Cyclic ketone (substance)\Donepezil hydrochloride (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Donepezil hydrochloride (substance)	Is a	Donepezil (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Has disposition	Acetylcholine receptor agonist (disposition)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Has disposition	Cholinesterase inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Has disposition	Centrally acting acetylcholinesterase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is modification of (attribute)	Donepezil (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Piperidine derivative	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Substance with centrally acting acetylcholinesterase inhibitor mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Parasympathomimetic agent (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Substance with sigma-1 receptor agonist mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Has disposition	Sigma-1 receptor agonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Cyclic ketone (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride (substance)	Is a	Central nervous system agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing donepezil hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil 1mg/mL oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil 5mg orally disintegrating tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil 10mg orally disintegrating tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Aricept odt 5mg orally disintegrating tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride 23 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil hydrochloride 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 5 mg oral tablet	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 23 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 23 mg oral tablet	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride monohydrate	Is a	False	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 23 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 5 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride monohydrate	Is modification of (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely donepezil hydrochloride 10 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 1 mg/mL oral solution	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil hydrochloride 1 mg/mL oral solution	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely donepezil hydrochloride 5 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely donepezil hydrochloride 5 milligram/1 each conventional release orodispersible tablet (clinical drug)	Has basis of strength substance (attribute)	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil (as donepezil hydrochloride) 5 mg and memantine (as memantine hydrochloride) 10 mg oral tablet	Has precise active ingredient	True	Donepezil hydrochloride (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461034013	Donepezil hydrochloride (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480971010	Donepezil hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461034013	Donepezil hydrochloride (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461034013	Donepezil hydrochloride (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480971010	Donepezil hydrochloride	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1480971010	Donepezil hydrochloride	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
46141000188116	donépézil chlorhydrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
807141000172111	chlorhydrate de donépézil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
46141000188116	donépézil chlorhydrate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
807141000172111	chlorhydrate de donépézil	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module