386858008: Tramadol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with glutamate receptor antagonist mechanism of action (substance)\NMDA receptor antagonist\Tramadol (substance)
\Substance categorized by disposition\Receptor agonist\Opioid receptor agonist\Tramadol (substance)

\Drug or medicament (substance)\Opioid receptor agonist\Tramadol (substance)
\Drug or medicament (substance)\Analgesic (substance)\Tramadol (substance)
\Drug or medicament (substance)\Central nervous system agent (substance)\Psychoactive substance\Central depressant\Tramadol (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Substance with ether structure (substance)\Tramadol (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tramadol (substance)	Is a	Non-opioid analgesics	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	Opioid receptor agonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	NMDA receptor antagonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Has disposition	N-methyl-D-aspartate receptor antagonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Has disposition	Opioid receptor agonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	Central depressant	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	Drug pseudoallergen by function	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	Analgesic (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	éther	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol (substance)	Is a	Substance with ether structure (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tramadol-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol measurement	Component	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride 100mg/2mL injection (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 100mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 150mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 200mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50mg soluble tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50mg m/r capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 100mg m/r capsule (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 150mg m/r capsule (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 200mg m/r capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50mg/sachet powder (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 100 mg effervescent powder for oral solution sachet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 75mg m/r tablet (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 300mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 400mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Acetaminophen + tramadol hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release orodispersible tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride	Is a	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing paracetamol and tramadol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Measurement of tramadol in urine specimen	Component	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Allergy to tramadol	Causative agent (attribute)	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to tramadol	Causative agent (attribute)	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol hydrochloride	Is modification of (attribute)	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol hydrochloride 300mg prolonged-release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Tramadol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	False	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing paracetamol and tramadol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only tramadol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only paracetamol and tramadol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only paracetamol and tramadol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Allergy to tramadol	Causative agent (attribute)	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only tramadol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only tramadol in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Tramadol-containing product in oromucosal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only tramadol in oromucosal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Adverse reaction caused by tramadol (disorder)	Causative agent (attribute)	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dexketoprofen and tramadol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dexketoprofen- and tramadol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dexketoprofen and tramadol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dexketoprofen- and tramadol-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Measurement of tramadol in urine specimen	Component	True	Tramadol (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461036010	Tramadol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480973013	Tramadol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461036010	Tramadol (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461036010	Tramadol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480973013	Tramadol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1480973013	Tramadol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
53231000195116	tramadol	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
67371000195111	Tramadol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846961000172119	tramadol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
846961000172119	tramadol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
53231000195116	tramadol	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
67371000195111	Tramadol	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module