386919002: Rituximab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Rituximab (substance)

\Drug or medicament (substance)\Immunosuppressant (substance)\Rituximab (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Rituximab (substance)
\Drug or medicament (substance)\Monoclonal antibody\Rituximab (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Rituximab (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Rituximab (substance)

\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Rituximab (substance)
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Rituximab (substance)
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Rituximab (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Rituximab (substance)	Is a	Monoclonal antibody	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab (substance)	Is a	agent d'anticorps monoclonal	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab (substance)	Has disposition	Immunomodulator (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab (substance)	Is a	anticorps monoclonal chimérique souris-humain d'isotype IgG	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Rituximab-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rituximab 10mg/mL injection concentrate 10mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab 10mg/mL infusion concentrate 50mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab 500mg infusion concentrate vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Rituximab 100mg infusion concentrate vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Adverse reaction caused by rituximab administered by infusion (disorder)	Causative agent (attribute)	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing rituximab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
R-ICE chemotherapy regimen	Direct substance	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	7
R-CHOP chemotherapy regimen	Direct substance	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	6
Rituximab therapy (procedure)	Direct substance	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely rituximab 100 milligram/10 milliliter conventional release solution for infusion vial	Has basis of strength substance (attribute)	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rituximab 100 milligram/10 milliliter conventional release solution for infusion vial	Has precise active ingredient	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rituximab 500 milligram/50 milliliter conventional release solution for infusion vial	Has basis of strength substance (attribute)	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rituximab 500 milligram/50 milliliter conventional release solution for infusion vial	Has precise active ingredient	False	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rituximab only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only rituximab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rituximab 10 milligram/1 milliliter conventional release solution for infusion (clinical drug)	Has precise active ingredient	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rituximab 10 milligram/1 milliliter conventional release solution for infusion (clinical drug)	Has basis of strength substance (attribute)	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
R-CEOP (rituximab, cyclophosphamide, etoposide, vincristine, prednisone) antineoplastic chemotherapy	Direct substance	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Rituximab 10 mg/mL solution for injection	Has precise active ingredient	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rituximab 10 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rituximab 10 mg/mL solution for infusion and/or injection	Has precise active ingredient	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rituximab 10 mg/mL solution for infusion and/or injection	Has basis of strength substance (attribute)	True	Rituximab (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461097016	Rituximab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481033012	Rituximab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461097016	Rituximab (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461097016	Rituximab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481033012	Rituximab	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1481033012	Rituximab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
54531000195117	rituximab	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
68901000195119	Rituximab	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
193051000077119	rituximab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
193051000077119	rituximab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
54531000195117	rituximab	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
68901000195119	Rituximab	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module