Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Tacrolimus-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 5 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 5mg/mL infusion concentrate 1mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 500 microgram oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 5mg/mL injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 0.03% ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus [skin] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus monohydrate 0.03% ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus monohydrate 0.1% ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Topical tacrolimus |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing tacrolimus in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5mg/mL injection solution 1mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 5mg/1mL infusion concentrate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 0.1% ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 5mg/mL infusion concentrate 1mL ampule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 5mg/1mL infusion concentrate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Blood tacrolimus level (procedure) |
Component |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Serum tacrolimus measurement (procedure) |
Component |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tacrolimus measurement (procedure) |
Component |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Nephropathy induced by tacrolimus |
Causative agent (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 750microgram modified-release tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 4mg modified-release tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 1mg modified-release tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus therapy (procedure) |
Direct substance |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Tacrolimus monohydrate (substance) |
Is a |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg oral capsule |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 500 microgram oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 500 microgram oral capsule |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 4mg prolonged-release oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 1mg prolonged-release oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus 750microgram prolonged-release orale tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg oral capsule |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 500 microgram oral capsule |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment |
Has basis of strength substance (attribute) |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment |
Has basis of strength substance (attribute) |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion ampule |
Has precise active ingredient |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion ampule |
Has basis of strength substance (attribute) |
False |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus monohydrate (substance) |
Is modification of (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tacrolimus-containing product in cutaneous dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing only tacrolimus (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus only product in cutaneous dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing only tacrolimus in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg/mL solution for infusion |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg/mL solution for infusion |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for injection (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for injection (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 1 mg/g cutaneous ointment |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 1 mg/g cutaneous ointment |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 sachet granules for conventional release oral suspension (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 sachet granules for conventional release oral suspension (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 200 microgram granules for oral suspension sachet |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 200 microgram granules for oral suspension sachet |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg prolonged-release oral capsule |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 5 mg prolonged-release oral capsule |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 4 mg prolonged-release oral tablet |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 4 mg prolonged-release oral tablet |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 3 milligram/1 each prolonged-release oral capsule (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 3 milligram/1 each prolonged-release oral capsule (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral tablet (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral tablet (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 750 microgram prolonged-release oral tablet |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 750 microgram prolonged-release oral tablet |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 500 microgram prolonged-release oral capsule |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus 500 microgram prolonged-release oral capsule |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral capsule (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral capsule (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug) |
Has precise active ingredient |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug) |
Has basis of strength substance (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Tacrolimus anhydrous (substance) |
Is modification of (attribute) |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Blood tacrolimus level (procedure) |
Component |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Serum tacrolimus measurement (procedure) |
Component |
True |
Tacrolimus |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |