387008005: Rofecoxib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Rofecoxib (substance)

\Drug or medicament (substance)\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Rofecoxib (substance)
\Drug or medicament (substance)\Analgesic (substance)\Non-opioid analgesics\Non-steroidal anti-inflammatory agent\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)\Rofecoxib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Sulfur and/or sulfur compound\Sulfur compound\Sulfone (substance)\Rofecoxib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Rofecoxib (substance)	Is a	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Rofecoxib (substance)	Has disposition	Cyclooxygenase-2 inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Rofecoxib (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Rofecoxib (substance)	Is a	Sulfone (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing rofecoxib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Rofecoxib 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely rofecoxib 2.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Rofecoxib 25mg/5mL oral suspension (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Rofecoxib 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing rofecoxib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 12.5 mg oral tablet	Has basis of strength substance (attribute)	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 25 mg oral tablet	Has basis of strength substance (attribute)	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 50 mg oral tablet	Has basis of strength substance (attribute)	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 25 mg oral tablet	Has precise active ingredient	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 50 mg oral tablet	Has precise active ingredient	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 12.5 mg oral tablet	Has precise active ingredient	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rofecoxib 2.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	Has precise active ingredient	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely rofecoxib 2.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	Has basis of strength substance (attribute)	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 25mg/5mL oral suspension (substance)	Has basis of strength substance (attribute)	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib 25mg/5mL oral suspension (substance)	Has precise active ingredient	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Rofecoxib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only rofecoxib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Rofecoxib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461186018	Rofecoxib (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481122012	Rofecoxib	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461186018	Rofecoxib (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461186018	Rofecoxib (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481122012	Rofecoxib	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1481122012	Rofecoxib	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
371361000195117	rofecoxib	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3337461001000115	Rofecoxib	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
838651000172114	rofécoxib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
838651000172114	rofécoxib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
371361000195117	rofecoxib	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3337461001000115	Rofecoxib	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module