387014003: Sirolimus (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Sirolimus (substance)
\Substance categorized by disposition\Substance with antibacterial mechanism of action (substance)\Substance with macrolide structure and antibacterial mechanism of action (substance)\Sirolimus (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Sirolimus (substance)

\Drug or medicament (substance)\Anti-infective agent (substance)\Substance with antibacterial mechanism of action (substance)\Substance with macrolide structure and antibacterial mechanism of action (substance)\Sirolimus (substance)
\Drug or medicament (substance)\Immunosuppressant (substance)\Sirolimus (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Sirolimus (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Amide\Lactam\Sirolimus (substance)

\Organic compound\Substance with ether structure (substance)\Sirolimus (substance)
\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Lactam\Sirolimus (substance)
\Organic compound\Lactone (substance)\Macrolide (substance)\Substance with macrolide structure and antibacterial mechanism of action (substance)\Sirolimus (substance)
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Amide\Lactam\Sirolimus (substance)
\Organic compound\Ketone\Cyclic ketone (substance)\Sirolimus (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Sirolimus (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	classe d'allergènes	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Macrolide immunosuppressant	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Protein kinase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Has disposition	Protein kinase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Macrolide (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Has disposition	Immunomodulator (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Cyclic ketone (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Lactam	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Substance with macrolide structure and antibacterial mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Has disposition	Antibacterial (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	éther	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus (substance)	Is a	Substance with ether structure (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Glatiramer-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing sirolimus (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sirolimus 1 milligram/1 milliliter conventional release oral solution (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 1mg/sachet oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 2mg/sachet oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 1mg/mL solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Glatiramer acetate 20mg/vial injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Glatiramer acetate 20 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Glatiramer acetate 20mg/vial injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Sirolimus 140mcg/cc drug eluting stent	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Blood sirolimus measurement	Component	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Measurement of sirolimus (procedure)	Component	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus therapy (procedure)	Direct substance	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Sirolimus 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus 1 mg oral tablet	Has basis of strength substance (attribute)	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus 2 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus 2 mg oral tablet	Has basis of strength substance (attribute)	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing sirolimus in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus 2 mg oral tablet	Has precise active ingredient	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus 1 mg oral tablet	Has precise active ingredient	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sirolimus 1 milligram/1 milliliter conventional release oral solution (clinical drug)	Has precise active ingredient	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sirolimus 1 milligram/1 milliliter conventional release oral solution (clinical drug)	Has basis of strength substance (attribute)	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only sirolimus (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only sirolimus in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sirolimus 140 microgram/cm2 drug eluting stent (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Blood sirolimus measurement	Component	True	Sirolimus (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461192012	Sirolimus (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481128011	Sirolimus	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2672939010	Rapamycin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461192012	Sirolimus (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461192012	Sirolimus (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481128011	Sirolimus	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1481128011	Sirolimus	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2672939010	Rapamycin	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2672939010	Rapamycin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
59021000195112	sirolimus	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74191000195112	Sirolimus	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
840391000172113	sirolimus	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
840391000172113	sirolimus	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
59021000195112	sirolimus	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74191000195112	Sirolimus	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module