387160004: Captopril (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\...

\Substance with renin-angiotensin system inhibitor mechanism of action (substance)\Angiotensin-converting enzyme inhibitor\Captopril (substance)

\Substance with hydrolase inhibitor mechanism of action (substance)\Peptide hydrolase inhibitor\Angiotensin-converting enzyme inhibitor\Captopril (substance)

\Drug or medicament (substance)\agent cardiovasculaire\Hypotensive agent (substance)\Substance with renin-angiotensin system inhibitor mechanism of action (substance)\Angiotensin-converting enzyme inhibitor\Captopril (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amine and/or amine derivative\Pyrrolidine\Captopril (substance)

\Organic compound\Organic acid and/or organic acid derivative (substance)\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic acid\Captopril (substance)
\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Pyrrolidine\Captopril (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Captopril (substance)	Is a	Angiotensin-converting enzyme inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril (substance)	Is a	Pyrrolidine	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril (substance)	Is a	Carboxylic acid	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril (substance)	Has disposition	Angiotensin-converting enzyme inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Captopril measurement	Component	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Fetal captopril/enalapril syndrome	Causative agent (attribute)	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril allergy	Causative agent (attribute)	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril 25 mg and hydrochlorothiazide 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril 50 mg and hydrochlorothiazide 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely captopril 12.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril+diuretic	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely captopril 100 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril 25 mg and hydrochlorothiazide 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely captopril 25 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril 50 mg and hydrochlorothiazide 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril + hydrochlorothiazide 50mg/25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Co-zidocapt 25mg/12.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Co-zidocapt 50mg/25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Co-zidocapt	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing captopril and hydrochlorothiazide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Co-zidocapt 25mg/12.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Co-zidocapt 50mg/25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Captopril adverse reaction	Causative agent (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Non-allergic hypersensitivity to captopril (finding)	Causative agent (attribute)	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Non-allergic hypersensitivity to captopril (finding)	Causative agent (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg and hydrochlorothiazide 12.5 mg oral tablet	Has basis of strength substance (attribute)	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely captopril 12.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg oral tablet	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg oral tablet	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 100 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 100 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 25 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Captopril 25 mg and hydrochlorothiazide 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg and hydrochlorothiazide 12.5 mg oral tablet	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg and hydrochlorothiazide 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg and hydrochlorothiazide 15 mg oral tablet	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 25 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 25 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg and hydrochlorothiazide 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg and hydrochlorothiazide 15 mg oral tablet	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg and hydrochlorothiazide 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg and hydrochlorothiazide 25 mg oral tablet	Has basis of strength substance (attribute)	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg oral tablet	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg oral tablet	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 25 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely captopril 100 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg and hydrochlorothiazide 15 mg oral tablet	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing captopril and hydrochlorothiazide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg and hydrochlorothiazide 12.5 mg oral tablet	Has precise active ingredient	False	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Captopril 25 mg and hydrochlorothiazide 15 mg oral tablet	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 50 mg and hydrochlorothiazide 25 mg oral tablet	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only captopril (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril and hydrochlorothiazide only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril and hydrochlorothiazide only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only captopril in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Captopril 25 mg and hydrochlorothiazide 12.5 mg oral tablet	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely captopril 25 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Captopril (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461338016	Captopril (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481268016	Captopril	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461338016	Captopril (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461338016	Captopril (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481268016	Captopril	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1481268016	Captopril	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
59791000195113	captopril	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
75161000195115	Captopril	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
797511000172119	captopril	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
797511000172119	captopril	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
59791000195113	captopril	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
75161000195115	Captopril	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module