Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Buprenorphine measurement |
Component |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine poisoning (disorder) |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Accidental buprenorphine poisoning |
Causative agent (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Intentional buprenorphine poisoning |
Causative agent (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
intoxication par la buprénorphine d'intention indéterminée |
Causative agent (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine adverse reaction |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Allergy to buprenorphine |
Causative agent (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine overdose |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Accidental buprenorphine overdose |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Intentional buprenorphine overdose (disorder) |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
surdose de buprénorphine d'intention indéterminée |
Causative agent (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing buprenorphine (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 400micrograms sublingual tablet (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 2mg sublingual tablet (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing precisely buprenorphine (as buprenorphine hydrochloride) 8 milligram/1 each conventional release sublingual tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine (as buprenorphine hydrochloride) 200 microgram sublingual tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
buprénorphine 300 microgrammes/mL, ampoule de 1 mL de solution pour injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 70micrograms/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 52.5micrograms/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 35micrograms/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine hydrochloride + naloxone hydrochloride |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine hydrochloride 2mg + naloxone hydrochloride 0.5mg sublingual tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine hydrochloride 8mg + naloxone hydrochloride 2mg sublingual tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Urine buprenorphine level |
Component |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Buprenorphine 35micrograms/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 52.5micrograms/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 70micrograms/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Serum buprenorphine level |
Component |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Plasma buprenorphine level (procedure) |
Component |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Buprenorphine hydrochloride (substance) |
Is a |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Accidental buprenorphine poisoning |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Intentional buprenorphine poisoning |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing buprenorphine and naloxone (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing buprenorphine in topical dosage form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing buprenorphine in oropharyngeal dosage form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing buprenorphine in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Norbuprenorphine (substance) |
Is a |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 20 microgram/hour prolonged-release transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 10 microgram/hour prolonged-release transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 5microgram/hour transdermal patch |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing buprenorphine and naloxone in oropharyngeal dosage form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Allergy to buprenorphine |
Causative agent (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Buprenorphine hydrochloride (substance) |
Is modification of (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Buprenorphine 400micrograms sublingual tablet (substance) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine (as buprenorphine hydrochloride) 8 milligram/1 each conventional release sublingual tablet (clinical drug) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine (as buprenorphine hydrochloride) 200 microgram sublingual tablet |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 2mg sublingual tablet (substance) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing buprenorphine in transdermal dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine (as buprenorphine hydrochloride) 300 microgram/1 milliliter conventional release solution for injection ampule |
Has basis of strength substance (attribute) |
False |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 35 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 35 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 52.5 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 52.5 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 70 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 70 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing buprenorphine in cutaneous dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine-containing product in oromucosal dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine and naloxone only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing only buprenorphine in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine and naloxone only product in oromucosal dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing only buprenorphine in cutaneous dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine only product in oromucosal dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing only buprenorphine in transdermal dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine (as buprenorphine hydrochloride) 300 microgram/1 milliliter conventional release solution for injection (clinical drug) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Allergy to buprenorphine |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 20 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 20 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 10 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 10 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 2 milligram and naloxone hydrochloride 500 microgram/1 each conventional release sublingual tablet (clinical drug) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Product containing precisely buprenorphine 2 milligram and naloxone hydrochloride 500 microgram/1 each conventional release sublingual tablet (clinical drug) |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Buprenorphine- and naloxone-containing product in oromucosal dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Buprenorphine (as buprenorphine hydrochloride) 8 mg and naloxone hydrochloride 2 mg sublingual tablet |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Drug addiction therapy using buprenorphine |
Using substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Drug addiction therapy using buprenorphine and naloxone |
Using substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Buprenorphine dependence (disorder) |
Causative agent (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 5 microgram/hour prolonged-release transdermal patch |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Buprenorphine 5 microgram/hour prolonged-release transdermal patch |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 15 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has precise active ingredient |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing precisely buprenorphine 15 microgram/1 hour prolonged-release transdermal patch (clinical drug) |
Has basis of strength substance (attribute) |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Serum buprenorphine level |
Component |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Plasma buprenorphine level (procedure) |
Component |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Urine buprenorphine level |
Component |
True |
Buprenorphine |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |