387220006: Phenytoin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with cellular transport inhibitor mechanism of action (substance)\Substance with sodium channel blocker mechanism of action (substance)\Phenytoin (substance)

\Drug or medicament (substance)\agent cardiovasculaire\Antiarrhythmic agent (substance)\Class I antiarrhythmic agent\Class Ib antiarrhythmic agent (substance)\Phenytoin (substance)
\Drug or medicament (substance)\Central nervous system agent (substance)\Anticonvulsant (substance)\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)

\Diagnostic substance (substance)\Patch test substance\Extended series patch test substance\Shoe series patch test substance\Imidazolidinone (substance)\Phenytoin (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Azole (substance)\Imidazole\Hydantoin and/or hydantoin derivative (substance)\Hydantoin derivative\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)

\Amide and/or amide derivative\Imidazolidinone (substance)\Phenytoin (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Azole (substance)\Imidazole\Hydantoin and/or hydantoin derivative (substance)\Hydantoin derivative\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)
\Organic compound\Organic nitrogen compound\Azole (substance)\Imidazole\Hydantoin and/or hydantoin derivative (substance)\Hydantoin derivative\Hydantoin derivative anticonvulsant (substance)\Phenytoin (substance)
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Imidazolidinone (substance)\Phenytoin (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Phenytoin (substance)	Is a	Hydantoin (substance)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin (substance)	Is a	Class Ib antiarrhythmic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin (substance)	Is a	Hydantoin derivative anticonvulsant (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin (substance)	Is a	Imidazolidinone (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin (substance)	Is a	Substance with sodium channel blocker mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin (substance)	Has disposition	Sodium channel blocker	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Phenytoin, free measurement	Component	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Gingival hypertrophy due to diphenylhydantoin (disorder)	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Accidental overdose of phenytoin (disorder)	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin blood measurement	Component	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Serum phenytoin measurement	Component	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Accidental phenytoin poisoning	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Intentional phenytoin poisoning	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
intoxication par la phénytoïne d'intention indéterminée	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin adverse reaction	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Allergy to phenytoin	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin overdose	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Intentional phenytoin overdose	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
surdose de phénytoïne d'intention indéterminée	Causative agent (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 6 mg/mL oral suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin 90mg/5mL s/f suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin measurement	Component	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 25 mg/mL oral suspension	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Pentobarbital sodium 390mg/phenytoin sodium 50mg injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin sodium (substance)	Is a	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing phenytoin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Drug-induced lupus erythematosus caused by diphenylhydantoin (disorder)	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Poisoning by phenytoin	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental phenytoin poisoning	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Intentional phenytoin poisoning	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Purple glove syndrome	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 50 mg chewable tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to phenytoin	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Free phenytoin (substance)	Is a	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Free phenytoin (substance)	Is modification of (attribute)	False	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin sodium (substance)	Is modification of (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Phenytoin 50 mg chewable tablet	Has precise active ingredient	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 50 mg chewable tablet	Has basis of strength substance (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 18 mg/mL oral suspension	Has basis of strength substance (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 18 mg/mL oral suspension	Has precise active ingredient	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 6 mg/mL oral suspension	Has basis of strength substance (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 6 mg/mL oral suspension	Has precise active ingredient	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 25 mg/mL oral suspension	Has basis of strength substance (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin 25 mg/mL oral suspension	Has precise active ingredient	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Gingival hypertrophy due to diphenylhydantoin (disorder)	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
EMPACT (erythema multiforme associated with phenytoin and cranial radiation therapy) syndrome	Causative agent (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin calcium	Is modification of (attribute)	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Serum phenytoin measurement	Component	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Phenytoin blood measurement	Component	True	Phenytoin (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461398018	Phenytoin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481323014	Phenytoin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491929016	Diphenylhydantoin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491930014	DPH	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1461398018	Phenytoin (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461398018	Phenytoin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481323014	Phenytoin	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1481323014	Phenytoin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491929016	Diphenylhydantoin	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1491929016	Diphenylhydantoin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491930014	DPH	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1491930014	DPH	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
54681000195117	fenitoina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69061000195112	Phenytoin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
861951000172115	phénytoïne	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
861951000172115	phénytoïne	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
54681000195117	fenitoina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69061000195112	Phenytoin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module