387568001: Clozapine (substance)

SNOMED CT Concept\Substance\...

\Drug or medicament (substance)\Central nervous system agent (substance)\Psychoactive substance\Psychotropic agent (substance)\Anti-psychotic agent (substance)\Clozapine (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Piperazine and/or piperazine derivative (substance)\Piperazine derivative\Clozapine (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Clozapine (substance)	Is a	Atypical antipsychotic	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine (substance)	Is a	classe d'allergènes	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine (substance)	Is a	allergène médicamenteux	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine (substance)	Is a	pipérazine	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine (substance)	Is a	Piperazine derivative	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine (substance)	Is a	Anti-psychotic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Clozapine measurement	Component	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine poisoning (disorder)	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental clozapine poisoning	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Intentional clozapine poisoning	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
intoxication par la clozapine d'intention indéterminée	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine adverse reaction	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Allergy to clozapine	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine overdose	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Accidental clozapine overdose	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Intentional clozapine overdose (disorder)	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
surdose de clozapine d'intention indéterminée	Causative agent (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Clozapine 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing clozapine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 25 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing only clozapine orally disintegrating 100 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely clozapine 12.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Accidental clozapine poisoning	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Intentional clozapine poisoning	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing only clozapine orally disintegrating 12.5 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing only clozapine orally disintegrating 50 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Allergy to clozapine	Causative agent (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine therapy (procedure)	Direct substance	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely clozapine 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 25 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 100 mg oral tablet	Has basis of strength substance (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 25 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 25 mg/1 each oral tablet	Has basis of strength substance (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 100 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 100 mg/1 each oral tablet	Has basis of strength substance (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 12.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 50 mg oral tablet	Has basis of strength substance (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 12.5 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 12.5 mg/1 each oral tablet	Has basis of strength substance (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 50 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine orally disintegrating 50 mg/1 each oral tablet	Has basis of strength substance (attribute)	False	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 100 mg oral tablet	Has precise active ingredient	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 50 mg oral tablet	Has precise active ingredient	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 25 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only clozapine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Monitoring of clozapine therapy	Direct substance	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely clozapine 200 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely clozapine 200 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 50 mg/mL oral suspension	Has precise active ingredient	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Clozapine 50 mg/mL oral suspension	Has basis of strength substance (attribute)	True	Clozapine (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461746018	Clozapine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481658018	Clozapine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1461746018	Clozapine (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1461746018	Clozapine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481658018	Clozapine	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1481658018	Clozapine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
54791000195114	clozapina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69171000195119	Clozapin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
802221000172111	clozapine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
802221000172111	clozapine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
54791000195114	clozapina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69171000195119	Clozapin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module