396026002: Diethylstilbestrol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Sex hormone\Substance with estrogen receptor agonist mechanism of action (substance)\Diethylstilbestrol
\Substance categorized by disposition\Receptor agonist\Substance with estrogen receptor agonist mechanism of action (substance)\Diethylstilbestrol

\Drug or medicament (substance)\Hormone\Sex hormone\Substance with estrogen receptor agonist mechanism of action (substance)\Diethylstilbestrol

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Substance with phenol structure\Polyphenol (substance)\Diethylstilbestrol

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Diethylstilbestrol	Is a	estrogeno	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol	Has disposition	Estrogen	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol	Has disposition	Gonadal hormone	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol	Is a	Substance with estrogen receptor agonist mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol	Has disposition	Estrogen receptor agonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol	Is a	Polyphenol (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Stilboestrol adverse reaction	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Stilbestrol allergy	Causative agent (attribute)	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Stilbestrol [gynecological use]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Stilbestrol+lactic acid 500micrograms/5% pessary	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Stilbestrol [malignancy]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol diphosphate preparation	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Diethylstilbestrol poisoning	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing diethylstilbestrol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing diethylstilbestrol and lactic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilboestrol measurement	Component	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Stilbestrol allergy	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Exposure to diethylstilbestrol	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
A malformation syndrome reported in offspring (children and grandchildren) of women exposed to diethylstilbestrol (DES) during pregnancy and is characterized by reproductive tract malformations, decreased fertility and increased risk of developing clear cell carcinoma of the vagina and cervix in young women. Reproductive malformations reported in DES syndrome include small, T-shaped uteri and other uterotubal anomalies that increase the risk of miscarriages in women and epididymal cysts, microphallus, cryptorchidism, or testicular hypoplasia in men. DES, a synthetic nonsteroidal estrogen was widely prescribed from 1940-1970 to prevent miscarriage.	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol 1 mg oral tablet	Has basis of strength substance (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Exposure to diethylstilbestrol in utero (event)	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Fosfestrol tetrasodium (substance)	Is modification of (attribute)	False	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol 1 mg oral tablet	Has precise active ingredient	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol and lactic acid only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Fosfestrol (substance)	Is modification of (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing only diethylstilbestrol in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Diethylstilbestrol-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
46,XX disorder of sex development caused by synthetic oral diethylstilbestrol	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Neonatal disorder caused by diethylstilbestrol transmitted via breast milk (disorder)	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Fetal disorder caused by diethylstilbestrol transmitted via placenta	Causative agent (attribute)	True	Diethylstilbestrol	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1469966015	Diethylstilbestrol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1477373011	Diethylstilbestrol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2475242013	Stilbestrol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1469966015	Diethylstilbestrol (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1469966015	Diethylstilbestrol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1476412015	Diethylstilboestrol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1477373011	Diethylstilbestrol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
1477373011	Diethylstilbestrol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2475032016	Stilboestrol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2475242013	Stilbestrol	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2475242013	Stilbestrol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
805861000172112	diéthylstilbestrol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
805861000172112	diéthylstilbestrol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module