406458000: Memantine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with glutamate receptor antagonist mechanism of action (substance)\NMDA receptor antagonist\Memantine

\Drug or medicament (substance)\Central nervous system agent (substance)\Memantine

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Alicyclic compound (substance)\Memantine

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2004. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Memantine	Is a	Central nervous system agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine	Is a	NMDA receptor antagonist	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine	Is a	Alicyclic compound (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine	Has disposition	N-methyl-D-aspartate receptor antagonist (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine	Is a	agent antidémence	false	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing memantine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing memantine hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride 10mg/g oral drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine 2mg/mL oral solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine 10mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride (substance)	Is a	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Donepezil- and memantine-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Donepezil- and memantine-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Memantine hydrochloride 7 mg prolonged-release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride 14 mg prolonged-release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride 21 mg prolonged-release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride 28 mg prolonged-release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Memantine hydrochloride (substance)	Is modification of (attribute)	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing memantine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only donepezil and memantine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Memantine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only donepezil and memantine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Memantine only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Donepezil (as donepezil hydrochloride) 5 mg and memantine (as memantine hydrochloride) 10 mg oral tablet	Has basis of strength substance (attribute)	True	Memantine	Inferred relationship	Existential restriction modifier (core metadata concept)	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
2150288017	Memantine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2158110013	Memantine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2150288017	Memantine (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2150288017	Memantine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2158110013	Memantine	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2158110013	Memantine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
58781000195116	memantina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
73951000195116	Memantin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
823481000172114	mémantine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
823481000172114	mémantine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
58781000195116	memantina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
73951000195116	Memantin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module