426725002: Aliskiren (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\...

\Substance with renin-angiotensin system inhibitor mechanism of action (substance)\Renin inhibitor\Aliskiren

\Substance with hydrolase inhibitor mechanism of action (substance)\Peptide hydrolase inhibitor\Proteinase inhibitor\Aspartic proteinase inhibitor\Renin inhibitor\Aliskiren

\Drug or medicament (substance)\agent cardiovasculaire\Hypotensive agent (substance)\Substance with renin-angiotensin system inhibitor mechanism of action (substance)\Renin inhibitor\Aliskiren

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Azole (substance)\Tetrazole (substance)\Aliskiren

\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Azole (substance)\Tetrazole (substance)\Aliskiren
\Organic compound\Organic nitrogen compound\Azole (substance)\Tetrazole (substance)\Aliskiren

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2007. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Aliskiren	Is a	Renin inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren	Is a	Tetrazole (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren	Has disposition	Renin inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Aliskiren fumarate (substance)	Is a	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing aliskiren (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing aliskiren and hydrochlorothiazide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren- and valsartan-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and valsartan 320 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren 150 milligram and valsartan 160 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing aliskiren and amlodipine and hydrochlorothiazide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and amlodipine (as amlodipine besilate) 10 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and amlodipine (as amlodipine besilate) 10 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren (as aliskiren fumarate) 300 mg and amlodipine (as amlodipine besilate) 5 mg and hydrochlorothiazide 25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and amlodipine (as amlodipine besilate) 5 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren (as aliskiren fumarate) 150 mg and amlodipine (as amlodipine besilate) 5 mg and hydrochlorothiazide 12.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and valsartan 160 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and valsartan 320 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and valsartan 320 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and valsartan 160 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and valsartan 160 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	Has basis of strength substance (attribute)	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aliskiren- and valsartan-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing aliskiren in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aliskiren- and hydrochlorothiazide-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 150 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and valsartan 320 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 150 milligram and valsartan 160 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren 300 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet	Has precise active ingredient	False	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aliskiren fumarate (substance)	Is modification of (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)
Aliskiren and hydrochlorothiazide only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only aliskiren and valsartan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only aliskiren and amlodipine and hydrochlorothiazide (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing only aliskiren (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only aliskiren and hydrochlorothiazide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only aliskiren and valsartan in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only aliskiren in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aliskiren (as aliskiren fumarate) 150 mg oral tablet	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Aliskiren (as aliskiren fumarate) 150 mg and amlodipine (as amlodipine besilate) 5 mg and hydrochlorothiazide 12.5 mg oral tablet	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and amlodipine (as amlodipine besilate) 10 milligram and hydrochlorothiazide 25 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Aliskiren (as aliskiren fumarate) 300 mg and amlodipine (as amlodipine besilate) 5 mg and hydrochlorothiazide 25 mg oral tablet	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and amlodipine (as amlodipine besilate) 5 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing only aliskiren and amlodipine and hydrochlorothiazide in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and amlodipine (as amlodipine besilate) 10 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Aliskiren- and amlodipine- and hydrochlorothiazide-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Aliskiren (as aliskiren fumarate) 150 mg and hydrochlorothiazide 25 mg oral tablet	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aliskiren (as aliskiren fumarate) 300 mg and hydrochlorothiazide 25 mg oral tablet	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren (as aliskiren fumarate) 150 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren (as aliskiren fumarate) 300 milligram and hydrochlorothiazide 12.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely aliskiren (as aliskiren fumarate) 150 milligram and valsartan 160 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Aliskiren (as aliskiren fumarate) 300 mg and valsartan 320 mg oral tablet	Has basis of strength substance (attribute)	True	Aliskiren	Inferred relationship	Existential restriction modifier (core metadata concept)	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
2663054014	Aliskiren (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2675069014	Aliskiren	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2663054014	Aliskiren (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2663054014	Aliskiren (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2675069014	Aliskiren	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
2675069014	Aliskiren	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
53811000195112	aliskiren	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
68751000195115	Aliskiren	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
789971000172114	aliskirène	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
789971000172114	aliskirène	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
53811000195112	aliskiren	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
68751000195115	Aliskiren	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module