446321003: Denosumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Substance with receptor activator of nuclear factor kappa-B ligand inhibitor mechanism of action (substance)\Denosumab

\Drug or medicament (substance)\Substance with receptor activator of nuclear factor kappa-B ligand inhibitor mechanism of action (substance)\Denosumab
\Drug or medicament (substance)\Monoclonal antibody\Denosumab

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Denosumab

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Denosumab

\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Denosumab
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Denosumab
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Denosumab

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2011. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

2879834015 Denosumab (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2881966015 Denosumab en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

2879834015 Denosumab (substance) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core

2879834015 Denosumab (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2881966015 Denosumab en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core

2881966015 Denosumab en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

52521000195111 denosumab it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

66871000195118 Denosumab de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

804441000172111 dénosumab fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

804441000172111 dénosumab fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

52521000195111 denosumab it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

66871000195118 Denosumab de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Denosumab	Is a	agent d'anticorps monoclonal	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Denosumab	Is a	Monoclonal antibody	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Denosumab	Has disposition	Receptor activator of nuclear factor kappa-B ligand inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Denosumab	Is a	Substance with receptor activator of nuclear factor kappa-B ligand inhibitor mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Denosumab 60 mg/mL solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing denosumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Denosumab therapy	Direct substance	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Allergy to denosumab (finding)	Causative agent (attribute)	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only denosumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Denosumab 60 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Denosumab 60 mg/mL solution for injection	Has precise active ingredient	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing denosumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only denosumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely denosumab 70 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely denosumab 70 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Denosumab	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets