Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Leukoencephalopathy due to copper deficiency |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cathepsin A-related arteriopathy, strokes, leukoencephalopathy |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Silent white matter disease due to vascular disease |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
A rare genetic neurological disorder characterized by infantile onset of progressive leukoencephalopathy, microcephaly, severe global developmental delay, and spasticity resulting in quadriparesis and posture deformation. Additional features include an abnormally exaggerated startle reflex, seizures, dystonia, and hypomimia or amimia, as well as progressive chest deformities and contractures of large and hyperextensibility of small joints, among others. Thin corpus callosum is a prominent feature in brain imaging, in addition to white matter abnormalities consistent with leukoencephalopathy. |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Early-onset calcifying leucoencephalopathy, skeletal dysplasia |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
PYCR2-related microcephaly, progressive leucoencephalopathy |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
6 |
Delayed post-hypoxic leukoencephalopathy |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
White matter disease due to microglioma |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
White matter disease due to anti-phospholipid syndrome (disorder) |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Toxic leukoencephalopathy (disorder) |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Stereotactic leucotomy |
Procedure site - Direct (attribute) |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Adult-onset progressive leukoencephalopathy, early-onset deafness (disorder) |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
A rare neurometabolic disease characterized by acute, reversible, and sometimes recurrent neurologic deterioration (including drowsiness, hypotonia, dysarthria, and ataxia) during a febrile illness. The condition is associated with reversible leukoencephalopathy and persistently increased urinary excretion (and sometimes cerebrospinal fluid concentration) mainly of alpha-ketoglutarate and N-acetylaspartate. |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
4 |
Developmental delay, immunodeficiency, leucoencephalopathy, hypohomocysteinemia syndrome |
Finding site |
True |
Cerebral white matter structure |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |