68523003: Cerebral white matter structure (body structure)

SNOMED CT Concept\Body structure\Anatomical or acquired body structure (body structure)\Anatomical structure\...

\Structure of anatomical cluster (body structure)\Structure of anatomical compartment (body structure)\Intracranial structure\Brain structure\Brain part\...

\Brain region\Structure of half of brain lateral to midsagittal plane (body structure)\Cerebral hemisphere structure (body structure)\Cerebral hemisphere part\Cerebral white matter structure
\Brain region\Structure of half of brain lateral to midsagittal plane (body structure)\Layer of cerebrum\Cerebral white matter structure
\Brain region\Supratentorial brain\Supratentorial brain part\The cerebrum is the regional structure of the brain, which is the adult equivalent of the forebrain or prosencephalon. It is constituted by the structural derivatives of the telencephalon and diencephalon including the cerebral hemispheres, epithalamus, thalamus, hypothalamus, lateral ventricles and third ventricle. This definition is harmonious with the Federation of Association of Anatomist Second Edition (2019) Part V Terminologia Anatomica.\Cerebral hemisphere structure (body structure)\Cerebral hemisphere part\Cerebral white matter structure
\Brain region\Supratentorial brain\Supratentorial brain part\The cerebrum is the regional structure of the brain, which is the adult equivalent of the forebrain or prosencephalon. It is constituted by the structural derivatives of the telencephalon and diencephalon including the cerebral hemispheres, epithalamus, thalamus, hypothalamus, lateral ventricles and third ventricle. This definition is harmonious with the Federation of Association of Anatomist Second Edition (2019) Part V Terminologia Anatomica.\Layer of cerebrum\Cerebral white matter structure

\Brain tissue structure\Structure of nervous tissue of brain\Structure of white matter of brain\Cerebral white matter structure

\Body tissue structure\Brain tissue structure\Structure of nervous tissue of brain\Structure of white matter of brain\Cerebral white matter structure
\Body tissue structure\Structure of nervous tissue\Central nervous tissue\Structure of nervous tissue of brain\Structure of white matter of brain\Cerebral white matter structure
\Body tissue structure\Structure of nervous tissue\Central nervous tissue\White matter structure of brain and spinal cord (body structure)\Structure of white matter of brain\Cerebral white matter structure

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cerebral white matter structure	Is a	Cerebral hemisphere white matter part	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	partie de	Entire cerebral hemisphere	false	Additional relationship (core metadata concept)	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	partie de	Entire brain and spinal cord (body structure)	false	Additional relationship (core metadata concept)	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	Is a	White matter structure of brain and spinal cord (body structure)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	Is a	Structure of telencephalon (body structure)	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	Is a	Cerebral hemisphere part	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	Laterality	Side	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	Is a	Layer of cerebrum	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Cerebral white matter structure	Is a	Structure of white matter of brain	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Structure of external capsule of brain (body structure)	Is a	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of white matter of occipital lobe	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of fimbria of hippocampus (body structure)	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Entire cerebral white matter	Is a	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of cerebral association fiber (body structure)	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of white matter of parietal lobe	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of external medullary lamina of thalamus	Is a	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of periventricular white matter (body structure)	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Stria medullaris structure	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of internal medullary lamina of thalamus	Is a	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of lateral medullary lamina	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of centrum semiovale	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of anterior commissure	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of medial medullary lamina	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of white matter of frontal lobe	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of alveus of hippocampus	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of white matter of temporal lobe	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Internal capsule structure	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Corpus callosum structure (body structure)	Is a	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of white matter of insula (body structure)	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Stereotactic leucotomy	Procedure site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Subacute hemorrhagic leukoencephalitis	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukotomy	Procedure site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Progressive multifocal leukoencephalopathy	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukoencephalopathy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
AIDS with progressive multifocal leukoencephalopathy	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Transorbital leukotomy	Procedure site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Cryoleucotomy	Procedure site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Acute hemorrhagic leukoencephalitis	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Subcortical leukoencephalopathy (disorder)	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Lobotomy of brain (procedure)	Procedure site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leucotomy NEC	Procedure site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Van Bogaert's sclerosing leukoencephalitis	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Progressive multifocal leucoencephalopathy with AIDS (acquired immunodeficiency syndrome)	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Cerebral hemisphere white matter part	Is a	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Structure of lenticular fasciculus	Is a	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)
Stereotactic leucotomy	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Leukotomy	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Transorbital leukotomy	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Cryoleucotomy	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Cryoleucotomy	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Lobotomy of brain (procedure)	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	4
Leucotomy NEC	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Cryoleucotomy	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Subacute hemorrhagic leukoencephalitis	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Progressive multifocal leucoencephalopathy with AIDS (acquired immunodeficiency syndrome)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukotomy	Procedure site - Direct (attribute)	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Subcortical leukoencephalopathy (disorder)	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Lobotomy of brain (procedure)	Procedure site - Direct (attribute)	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	4
Transorbital leukotomy	Procedure site - Direct (attribute)	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Van Bogaert's sclerosing leukoencephalitis	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Cryoleucotomy	Procedure site - Direct (attribute)	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Progressive multifocal leukoencephalopathy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Onset of disease between 2 and 5 years of age with characteristics of cerebello-spastic syndrome exacerbated by episodes of fever or head trauma leading to death after 5 to 10 years of disease evolution, diffuse involvement of the white matter on cerebral MRI with a CSF-like signal intensity (cavitation), a recessive autosomal mode of inheritance, neuropathologic findings consistent with a cavitating orthochromatic leukodystrophy with increased number of oligodendrocytes. This disease is linked to mutations in the five EIF2B genes encoding the five subunits of the eukaryotic initiation factor 2B (eIF2B), involved in the protein synthesis and its regulation under cellular stress.	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Onset of disease between 2 and 5 years of age with characteristics of cerebello-spastic syndrome exacerbated by episodes of fever or head trauma leading to death after 5 to 10 years of disease evolution, diffuse involvement of the white matter on cerebral MRI with a CSF-like signal intensity (cavitation), a recessive autosomal mode of inheritance, neuropathologic findings consistent with a cavitating orthochromatic leukodystrophy with increased number of oligodendrocytes. This disease is linked to mutations in the five EIF2B genes encoding the five subunits of the eukaryotic initiation factor 2B (eIF2B), involved in the protein synthesis and its regulation under cellular stress.	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Posterior reversible encephalopathy syndrome	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Subcortical leukoencephalopathy (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Hypomyelination and congenital cataract	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Hereditary diffuse leucoencephalopathy with spheroids	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Megalencephalic leucoencephalopathy with subcortical cysts	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Leucoencephalopathy with brainstem and spinal cord involvement and lactate elevation	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Progressive multifocal leucoencephalopathy co-occurrent with human immunodeficiency virus infection	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	4
Mitochondrial neurogastrointestinal encephalomyopathy syndrome (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Progressive cavitating leucoencephalopathy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukoencephalopathy co-occurrent with bilateral anterior temporal lobe cysts (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukoencephalopathy with metaphyseal chondrodysplasia syndrome	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Cystic leucoencephalopathy without megalencephaly	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
White matter disorder caused by infection (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Toxic leukoencephalopathy (disorder)	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Traumatic hemorrhage of cerebral white matter (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Traumatic hemorrhage of cerebral white matter (disorder)	Finding site	False	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
White matter disease (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
White matter disorder co-occurrent and due to cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
White matter disorder due to nutritional deficiency	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Leukoencephalopathy, dystonia, motor neuropathy syndrome	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Dementia with progressive multifocal leukoencephalopathy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Leukoencephalopathy with brain stem and spinal cord involvement and high lactate syndrome (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
White matter disorder due to vascular abnormality (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
White matter disorder due to ischemia	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
White matter disorder due to vitamin B12 deficiency	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Leukoencephalopathy, thalamus and brainstem anomalies, high lactate syndrome (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Marburg acute multiple sclerosis	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukoencephalopathy with mild cerebellar ataxia and white matter edema (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Human immunodeficiency virus leucoencephalopathy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Leukoencephalopathy, palmoplantar keratoderma syndrome	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Leucoencephalopathy with brainstem and spinal cord involvement and lactate elevation	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Cystic leucoencephalopathy without megalencephaly	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Autosomal recessive leukoencephalopathy, ischemic stroke, retinitis pigmentosa syndrome (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Collagen type IV alpha 1 chain related familial vascular leukoencephalopathy (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Progressive multifocal leucoencephalopathy co-occurrent with human immunodeficiency virus infection	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	5
Autosomal recessive spastic ataxia with leukoencephalopathy (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Neuroaxonal leukodystrophy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Van Bogaert's sclerosing leukoencephalitis	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Traumatic hemorrhage of cerebral white matter (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Onset of disease between 2 and 5 years of age with characteristics of cerebello-spastic syndrome exacerbated by episodes of fever or head trauma leading to death after 5 to 10 years of disease evolution, diffuse involvement of the white matter on cerebral MRI with a CSF-like signal intensity (cavitation), a recessive autosomal mode of inheritance, neuropathologic findings consistent with a cavitating orthochromatic leukodystrophy with increased number of oligodendrocytes. This disease is linked to mutations in the five EIF2B genes encoding the five subunits of the eukaryotic initiation factor 2B (eIF2B), involved in the protein synthesis and its regulation under cellular stress.	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Ovarioleukodystrophy	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	2
A rare genetic cerebral small vessel disease characterized by recurrent ischemic strokes, often with a predilection for the pons, with typical onset in the fourth or fifth decade of life. Patients present progressive cognitive and motor impairment with pyramidal, bulbar, and cerebellar symptoms, among others. Brain imaging shows multiple lacunar infarcts, typically with involvement of the pons, as well as variable leukoencephalopathy of the cerebral hemispheres.	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Leukoencephalopathy with calcifications and cysts (disorder)	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	4
Leukoencephalopathy due to copper deficiency	Finding site	True	Cerebral white matter structure	Inferred relationship	Existential restriction modifier (core metadata concept)	1

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Reference Sets

Lateralizable body structure reference set (foundation metadata concept)

Anatomy structure and entire association reference set (foundation metadata concept)

Anatomy structure and part association reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
113807010	Cerebral white matter	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
501040012	Cerebral white matter structure	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
808368013	Cerebral white matter structure (body structure)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
113807010	Cerebral white matter	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
113807010	Cerebral white matter	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
501040012	Cerebral white matter structure	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
501040012	Cerebral white matter structure	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
808368013	Cerebral white matter structure (body structure)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
808368013	Cerebral white matter structure (body structure)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core