710806008: Sofosbuvir (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Hepatitis C virus protein NS5B inhibitor\Sofosbuvir (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Nucleotidyltransferase inhibitor\Substance with RNA polymerase inhibitor mechanism of action (substance)\Sofosbuvir (substance)
\Substance categorized by disposition\Substance with antiviral mechanism of action (substance)\Hepatitis C virus protein NS5B inhibitor\Sofosbuvir (substance)
\Substance categorized by disposition\Substance with antiviral mechanism of action (substance)\Substance with RNA polymerase inhibitor mechanism of action (substance)\Sofosbuvir (substance)

\Drug or medicament (substance)\Anti-infective agent (substance)\Substance with antiviral mechanism of action (substance)\...

\Hepatitis C virus protein NS5B inhibitor\Sofosbuvir (substance)

\Substance with RNA polymerase inhibitor mechanism of action (substance)\Sofosbuvir (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\...

\Organic acid and/or organic acid derivative (substance)\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic ester (substance)\Sofosbuvir (substance)

\Ester\Carboxylic ester (substance)\Sofosbuvir (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2015. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Sofosbuvir (substance)	Is a	Substance with RNA polymerase inhibitor mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sofosbuvir (substance)	Is a	Hepatitis C virus protein NS5B inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sofosbuvir (substance)	Has disposition	Hepatitis C virus protein NS5B inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sofosbuvir (substance)	Has disposition	RNA polymerase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Sofosbuvir (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sofosbuvir (substance)	Is a	Nucleotidyltransferase inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Sofosbuvir (substance)	Is a	Carboxylic ester (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing sofosbuvir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing ledipasvir and sofosbuvir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing sofosbuvir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing ledipasvir and sofosbuvir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing simeprevir and sofosbuvir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing sofosbuvir and velpatasvir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir- and velpatasvir- and voxilaprevir-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing sofosbuvir and velpatasvir and voxilaprevir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir- and velpatasvir-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ledipasvir and sofosbuvir only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only simeprevir and sofosbuvir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Sofosbuvir only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only sofosbuvir and velpatasvir and voxilaprevir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only sofosbuvir and velpatasvir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only sofosbuvir and velpatasvir and voxilaprevir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing only ledipasvir and sofosbuvir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir and velpatasvir only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely ledipasvir 90 milligram and sofosbuvir 400 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely ledipasvir 90 milligram and sofosbuvir 400 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ledipasvir 45 mg and sofosbuvir 200 mg oral tablet	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ledipasvir 45 mg and sofosbuvir 200 mg oral tablet	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir 400 mg and velpatasvir 100 mg oral capsule	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir 400 mg and velpatasvir 100 mg oral capsule	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sofosbuvir 400 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sofosbuvir 400 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir 200 mg and velpatasvir 50 mg oral tablet	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Sofosbuvir 200 mg and velpatasvir 50 mg oral tablet	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sofosbuvir 400 milligram and velpatasvir 100 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sofosbuvir 400 milligram and velpatasvir 100 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sofosbuvir 400 milligram and velpatasvir 100 milligram and voxilaprevir 100 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely sofosbuvir 400 milligram and velpatasvir 100 milligram and voxilaprevir 100 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ledipasvir 33.75 mg and sofosbuvir 150 mg oral granules sachet	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Ledipasvir 33.75 mg and sofosbuvir 150 mg oral granules sachet	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely ledipasvir 45 milligram and sofosbuvir 200 milligram/1 sachet conventional release oral granules (clinical drug)	Has precise active ingredient	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely ledipasvir 45 milligram and sofosbuvir 200 milligram/1 sachet conventional release oral granules (clinical drug)	Has basis of strength substance (attribute)	True	Sofosbuvir (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3046366016	Sofosbuvir (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3046433016	Sofosbuvir	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3046366016	Sofosbuvir (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
3046366016	Sofosbuvir (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3046433016	Sofosbuvir	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
3046433016	Sofosbuvir	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
59071000195111	sofosbuvir	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74341000195118	Sofosbuvir	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
841531000172110	sofosbuvir	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
841531000172110	sofosbuvir	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
59071000195111	sofosbuvir	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
74341000195118	Sofosbuvir	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module