734620004: B-Raf inhibitor (disposition)

SNOMED CT Concept\Qualifier value\Disposition\Effector (disposition)\Compound or agent that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction US Library of Medicine MESH Descriptor data Accessed 20/01/2017\Transferase inhibitor (disposition)\Phosphotransferase inhibitor (disposition)\Protein kinase inhibitor (disposition)\B-Raf inhibitor

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3509626018 B-Raf inhibitor (disposition) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509627010 BRAF inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509628017 B-Raf inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509626018 B-Raf inhibitor (disposition) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509627010 BRAF inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509628017 B-Raf inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
B-Raf inhibitor	Is a	Protein kinase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Vemurafenib (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)
Dabrafenib (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)
Dabrafenib mesilate (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)
Substance with B-Raf inhibitor mechanism of action (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)
Trametinib (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)
Trametinib dimethyl sulfoxide (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)
Encorafenib (substance)	Has disposition	True	B-Raf inhibitor	Inferred relationship	Existential restriction modifier (core metadata concept)

This concept is not in any reference sets