736632003: Neratinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Neratinib (substance)

\Drug or medicament (substance)\Antineoplastic agent (substance)\Neratinib (substance)
\Drug or medicament (substance)\Quinoline\Neratinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Amine and/or amine derivative\Quinoline\Neratinib (substance)

\Nitrile\Neratinib (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Quinoline\Neratinib (substance)
\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Quinoline\Neratinib (substance)
\Organic compound\Organic nitrogen compound\Nitrile\Neratinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3520526014 Neratinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3520527017 Neratinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3520526014 Neratinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3520527017 Neratinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

372211000195115 neratinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

3340901001000111 Neratinib de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1135601000241117 nératinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1135601000241117 nératinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

372211000195115 neratinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

3340901001000111 Neratinib de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Neratinib (substance)	Is a	Quinoline	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Neratinib (substance)	Is a	Nitrile	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Neratinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Neratinib (substance)	Has disposition	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Neratinib (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Neratinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Neratinib maleate (substance)	Is a	False	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing neratinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Neratinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Neratinib maleate (substance)	Is modification of (attribute)	True	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing only neratinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Neratinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Neratinib (as neratinib maleate) 40 mg oral tablet	Has basis of strength substance (attribute)	True	Neratinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets