75777003: Cytokine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Mediator of immune response and inflammation (substance)\Mediator of immune response (substance)\Cytokine

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Glycoprotein (substance)\Cytokine

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide (substance)\Polypeptide\Protein\Glycoprotein (substance)\Cytokine

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cytokine	Is a	analyte immunologique	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Cytokine	Is a	Mediator of immune response (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Cytokine	Is a	Glycoprotein (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Cytokine	Has disposition	Immunomodulator (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Interleukin-2 assay (procedure)	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-6 assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-7 assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Mononuclear cell function assay (procedure)	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-3 assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Cytokine assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon gamma assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Intracellular free calcium assay (procedure)	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
TNF, Beta assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-8 assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Protein kinase C activity assay (procedure)	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alpha assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Lymphokine assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta assay (procedure)	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-4 assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-5 assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Tumor necrosis factor assay	Has measured component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interleukin-2 assay (procedure)	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-6 assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-7 assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Mononuclear cell function assay (procedure)	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
IL-3 assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Cytokine assay	Component	True	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Interferon gamma assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Intracellular free calcium assay (procedure)	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)	2
TNF, Beta assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-8 assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Protein kinase C activity assay (procedure)	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Interferon alpha assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Lymphokine assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)	3
Interferon assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta assay (procedure)	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-4 assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
IL-5 assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Tumor necrosis factor assay	Component	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing interferon gamma-1b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing interferon beta-1a (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta-1b-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing interferon alfa-2a (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing interferon alfa-2b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing cytokine (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing aldesleukin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing peginterferon alfa-2b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Product containing interferon beta (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon gamma-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Human interferon gamma-1b 100micrograms/0.5mL injection (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 10million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 5million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 3million iu injection (pdr for recon)+diluent (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 1million iu injection (pdr for recon)+diluent (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 6million iu/mL injection solution 3mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 18million iu/1mL injection solution (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta-1b 8million iu injection (pdr for recon)+diluent (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 1million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 4.5million iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 5million units injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 10million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 30million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 3million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 9million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 18million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 3million iu/1mL solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons 10million iu/1mL solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferons (2)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 6million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 4.5million iu/0.5mL prefilled syringe (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 12million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 9million iu/0.5mL prefilled syringe (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta-1a 6million iu injection (pdr for recon)+solvent (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 15million iu/1mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 25million iu/1mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 50million iu/1mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 25million iu/2.5mL injection solution (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta-1a 12million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta-1a 12million iu/0.5mL prefilled syringe (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 18million iu/0.6mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Peginterferon alfa-2b 50micrograms injection (pdr for recon)+solvent (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Peginterferon alfa-2b 80micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Peginterferon alfa-2b 100micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Peginterferon alfa-2b 150micrograms injection (pdr for recon)+solvent (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Peginterferon alfa-2b 120micrograms injection (pdr for recon)+solvent (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-n1-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Aldesleukin 18megaunits injection (pdr for recon) (substance)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 30000000iu solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 60million/iu solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 150mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 300mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 120mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 600mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 100.000mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2b 50mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-n3 human leu 5000000unt/mL injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 18000000iu/3mL injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 36000000iu/mL injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 3miu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 6miu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfa-2a 9miu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon alfacon-130mcg/mL injection solution 0.3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)
Interferon beta-1b 100mcg/ solution (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Existential restriction modifier (core metadata concept)

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Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
125852012	Cytokine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
816424012	Cytokine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
125852012	Cytokine	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
125852012	Cytokine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
816424012	Cytokine (substance)	en	Fully specified name	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
816424012	Cytokine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core