771596001: Tezacaftor (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with cystic fibrosis transmembrane conductance regulator potentiator mechanism of action (substance)\Tezacaftor (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Dioxole (substance)\Tezacaftor (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3706939018 Tezacaftor (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3706940016 Tezacaftor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3706939018 Tezacaftor (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3706940016 Tezacaftor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5521941000241117 tezacaftor fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

5521941000241117 tezacaftor fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tezacaftor (substance)	Is a	Dioxole (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tezacaftor (substance)	Has disposition	Cystic fibrosis transmembrane conductance regulator potentiator (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Tezacaftor (substance)	Is a	Substance with cystic fibrosis transmembrane conductance regulator potentiator mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing ivacaftor and tezacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Ivacaftor- and tezacaftor-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing only ivacaftor and tezacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Ivacaftor and tezacaftor only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Elexacaftor- and ivacaftor- and tezacaftor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing elexacaftor and ivacaftor and tezacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Elexacaftor and ivacaftor and tezacaftor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Elexacaftor and ivacaftor and tezacaftor only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Elexacaftor 50 mg and ivacaftor 37.5 mg and tezacaftor 25 mg oral tablet	Has precise active ingredient	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Elexacaftor 50 mg and ivacaftor 37.5 mg and tezacaftor 25 mg oral tablet	Has basis of strength substance (attribute)	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely elexacaftor 100 milligram and ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely elexacaftor 100 milligram and ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely ivacaftor 150 milligram and tezacaftor 100 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely ivacaftor 150 milligram and tezacaftor 100 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2
Product containing precisely ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tezacaftor (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	2

This concept is not in any reference sets