782976007: Lorlatinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Lorlatinib

\Drug or medicament (substance)\Antineoplastic agent (substance)\Lorlatinib

\Substance categorised by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Amide\Lactam\Lorlatinib

\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Lactam\Lorlatinib
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Amide\Lactam\Lorlatinib

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3757029013 Lorlatinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3757030015 Lorlatinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3757029013 Lorlatinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3757030015 Lorlatinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

368361000195118 lorlatinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1135001000241111 lorlatinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1135001000241111 lorlatinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

368361000195118 lorlatinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lorlatinib	Is a	Lactam	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Lorlatinib	Has disposition	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Lorlatinib	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Lorlatinib	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Lorlatinib	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing only lorlatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing lorlatinib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing lorlatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Lorlatinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely lorlatinib 100 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely lorlatinib 100 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely lorlatinib 25 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely lorlatinib 25 milligram/1 each conventional release oral tablet (clinical drug)	Has precise active ingredient	True	Lorlatinib	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets