870689004: Selumetinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Substance with mitogen-activated protein kinase kinase inhibitor mechanism of action (substance)\Selumetinib (substance)

\Drug or medicament (substance)\Antineoplastic agent (substance)\Selumetinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure\Organic compound\Organic cyclic compound\Heterocyclic compound (substance)\Benzimidazole\Selumetinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2020. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3970852010 Selumetinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3970853017 Selumetinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3970852010 Selumetinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3970853017 Selumetinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Selumetinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Existential restriction modifier (core metadata concept)
Selumetinib (substance)	Is a	Benzimidazole	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Selumetinib (substance)	Is a	Substance with mitogen-activated protein kinase kinase inhibitor mechanism of action (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Selumetinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Existential restriction modifier (core metadata concept)
Selumetinib (substance)	Has disposition	Mitogen-activated protein kinase kinase inhibitor	true	Inferred relationship	Existential restriction modifier (core metadata concept)

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing selumetinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Selumetinib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing selumetinib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Selumetinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely selumetinib 25 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	False	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely selumetinib 25 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	False	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely selumetinib 10 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	False	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely selumetinib 10 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	False	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Selumetinib sulfate	Is modification of (attribute)	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)
Selumetinib (as selumetinib hydrogen sulfate) 10 mg oral capsule	Has basis of strength substance (attribute)	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1
Product containing precisely selumetinib (as selumetinib hydrogen sulfate) 25 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Selumetinib (substance)	Inferred relationship	Existential restriction modifier (core metadata concept)	1

This concept is not in any reference sets