Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Serum dihydropyrimide dehydrogenase level |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Serum tissue transglutaminase level (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Cardiac markers (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Blood thiopurine methyltransferase level |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Bromelains (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thrombolytic agent |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Proteolytic enzyme preparation |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Laronidase-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with red blood cell enzyme mechanism of action |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with white blood cell enzyme mechanism of action |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
médicament thrombolytique |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme deficiency product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing drotrecogin alfa (activated) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Drotrecogin alfa (activated) 5mg powder for infusion solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Drotrecogin alfa 20 mg powder for solution for injection vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Miglustat-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing carglumic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Carglutamic acid 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Carglumic acid 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Miglustat 100 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Urokinase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing recombinant levo iduronidase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Laronidase 2.9mg/5mL injection solution 5mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing plasminogen activator (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme immunoassay method (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Carglutamic acid 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Microbial antigen assay by enzyme immunoassay method (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Product containing collagenase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Glycoasparaginase level |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing streptokinase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
streptokinase 1 500 000 U.I., fiole de poudre pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase 250,000iu injection (pdr for recon) (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
streptokinase 750 000 U.I., fiole de poudre pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Adverse reaction to enzymes |
Causative agent (attribute) |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Adverse reaction to enzymes NEC |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Adverse reaction to enzymes NOS |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase 600000iu/vial powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase 750000unt intravenous infusion vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase 1500000unt intravenous infusion vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase 250000unt intravenous infusion vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Proenzyme |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
A substance containing enzymes, mainly lipase, with amylase and protease, obtained from the pancreas of the hog. It is a cream-coloured, amorphous powder having a faint characteristic, but not offensive odour. Its greatest activities are in neutral or faintly alkaline media; more than traces of mineral acids or large amounts of alkali hydroxides make it inert. An excess of alkali carbonate also inhibits its action. Pancrelipase contains, in each mg, not less than 24 USP units of lipase activity, not less than 100 USP units of amylase activity, and not less than 100 USP units of protease activity. |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Holo-[acyl-carrier-protein] synthase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Chemonucleolysis (procedure) |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Injection of spinal intervertebral space with chymopapain |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Injection of spinal intervertebral space with chymotrypsin |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Lipoprotein associated phospholipase A₂ measurement (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Blood acid esterase measurement (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Oleate measurement |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Pancreatic enzyme (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Sebelipase alfa (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
GDP-mannose 3,5-epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Chondroitin-glucuronate 5-epimerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Muconate cycloisomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Aspartate racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Nocardicin-A epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alpha-methylacyl-CoA racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Mannose-6-phosphate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Triose-phosphate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Muconolactone delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Prostaglandin-A>1< delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
4-hydroxyphenylacetaldehyde-oxime isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Retinol isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Ribose isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Carboxyvinyl-carboxyphosphonate phosphorylmutase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Furylfuramide isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Farnesol 2-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
3-carboxy-cis,cis-muconate cycloisomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phenylpyruvate tautomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Protein disulfide-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Isopentenyl-diphosphate delta-isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
D-lyxose ketol-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Hydroxypyruvate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phosphoribosylanthranilate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Allantoin racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thiocyanate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Methylitaconate delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Galactose-6-phosphate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
ADP-glyceromanno-heptose 6-epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Glucuronate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Steroid delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Oxaloacetate tautomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Isopiperitenone delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Isobutyryl-CoA mutase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tetrahydroxypteridine cycloisomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Dopachrome isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Carboxy-cis,cis-muconate cyclase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Thromboxane synthase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Styrene-oxide isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Geranyl-diphosphate cyclase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Arginine racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Precorrin-8X methylmutase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Dodecenoyl -CoA delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
L-rhamnose isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Linoleate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phosphoenolpyruvate mutase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Lysine racemase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Phenylalanine racemase (ATP-hydrolysing) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|