Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Plant enzyme |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Clinically relevant enzymes with no Enzyme Commission designation |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Trapping enzyme |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme precursor |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with ligase mechanism of action (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Lyase |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with isomerase mechanism of action (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Clinically relevant isoenzyme (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme variant (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with transferase mechanism of action (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Oxidoreductase |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with hydrolase mechanism of action (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzymes A - L |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzymes M - Z (navigational concept) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Flavoprotein enzyme (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with oxidase mechanism of action (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Oxygenase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Glycosidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Nucleosidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Endopeptidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Exoribonuclease |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Endoribonuclease (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Metallocarboxypeptidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cysteine carboxypeptidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Omega peptidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cysteine proteinase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Aspartic proteinase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Metalloproteinase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with racemase mechanism of action (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Substance with mutase mechanism of action (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Pancreatic enzyme measurement |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Injection of spinal intervertebral space with chymopapain |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Measurement of liver enzyme (procedure) |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Injection of spinal intervertebral space with chymodiactin |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Medicinal enzyme adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase adverse reaction (disorder) |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Urokinase adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alteplase adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Anistreplase adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Bromelains adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Deoxyribonuclease adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Hyaluronidase adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Streptokinase streptodornase adverse reaction |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme measurement (procedure) |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Chemonucleolysis (procedure) |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Injection of spinal intervertebral space with chymotrypsin |
Direct substance |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Fecal trypsin, quantitative (procedure) |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cardiac enzymes/isoenzymes measurement |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Serum amylase (pancreatic) measurement |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme/specific protein level measurement (procedure) |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzymes/specific proteins NOS |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Liver enzymes NOS |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cardiac enzymes NOS |
Has measured component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Pegademase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Sacrosidase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alglucerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Enzyme radioimmunoassay |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Pancreatic enzyme measurement |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
3 |
Measurement of liver enzyme (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Enzyme measurement (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Fecal trypsin, quantitative (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cardiac enzymes/isoenzymes measurement |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Serum amylase (pancreatic) measurement |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
2 |
Enzyme/specific protein level measurement (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Enzymes/specific proteins NOS |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Liver enzymes NOS |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cardiac enzymes NOS |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing tissue plasminogen activator (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing reteplase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Anistreplase (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing enzyme (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Product containing tenecteplase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tenecteplase 8000iu(40mg) injection (pdr for recon)+solvent (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Tenecteplase 10,000iu(50mg) inj (pdr for recon)+solvent |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing alteplase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing urokinase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alteplase 50mg injection (pdr for recon)+diluent (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alteplase 20mg injection (pdr for recon)+diluent (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
alteplase 10 mg, fiole de poudre et solvant pour solution pour injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Reteplase 10units injection (pdr for recon)+diluent pack (substance) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing deoxyribonuclease (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Collagenase 250unit/g ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Reteplase, recombinant 10unt/vial powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alteplase 100mg powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Alteplase 1mg injection solution 1mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Anistreplase 30unt/vial powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Urokinase 50000u/mL injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Desoxyribonuclease + fibrinolysin 15000unt/25unt powder (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Desoxyribonuclease+fibrinolysin 6666unt/10unt ointment |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing recombinant human activated protein c |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Product containing drotrecogin alfa (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Drotrecogin alfa 5 mg powder for solution for injection vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Drotrecogin alfa 20mg powder for infusion solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Imiglucerase |
Is a |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Cholinesterase measurement |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Faecal elastase 1 level |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Blood immunoreactive trypsin level |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Roche number (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|
Blood erythrocyte porphobilinogen deaminase level (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
1 |
Serum dihydropyrimide dehydrogenase level |
Component |
False |
Enzyme |
Inferred relationship |
Existential restriction modifier (core metadata concept) |
|