126172005: Estradiol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Sex hormone (substance)\Substance with estrogen receptor agonist mechanism of action (substance)\Estradiol
\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Steroid hormone\Estradiol
\Substance categorized by disposition\Receptor agonist\Substance with estrogen receptor agonist mechanism of action (substance)\Estradiol

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Hormone\...

\Sex hormone (substance)\Substance with estrogen receptor agonist mechanism of action (substance)\Estradiol

\Steroid hormone\Estradiol

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Polycyclic compound (substance)\Steroid\...

\Estrane\Estradiol and/or estradiol derivative\Estradiol

\Steroid hormone\Estradiol

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

24201011 Estradiol en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

730100013 Estradiol (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3721927018 17-beta estradiol en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3722984013 E2 - estradiol en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Estradiol	Is a	Estrane	false	Inferred relationship	Some
Estradiol	Is a	Estradiol and/or estradiol derivative	true	Inferred relationship	Some
Estradiol	Is a	Estrogen	false	Inferred relationship	Some
Estradiol	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Estrogen	false	Inferred relationship	Some
Estradiol	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Gonadal hormone	false	Inferred relationship	Some
Estradiol	Is a	Substance with estrogen receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Estradiol	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Estrogen receptor agonist	true	Inferred relationship	Some
Estradiol	Is a	Steroid hormone	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Ethinylestradiol 35 microgram and norethisterone 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 50 microgram and norethisterone 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol + norethindrone acetate 20mcg/1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol + norethindrone acetate 30mcg/1.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 30 microgram and norgestrel 300 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely ethinylestradiol 50 microgram and norgestrel 500 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Fluid sample oestradiol level	Component	False	Estradiol	Inferred relationship	Some	2
Oestradiol 50micrograms/24hours vaginal ring	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing estrone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Norethisterone 170micrograms/24hours / Estradiol 50micrograms/24hours patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Norethisterone 250micrograms/24hours / Estradiol 50micrograms/24hours patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 35 microgram and norethisterone 750 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely estradiol valerate 2 milligram and medroxyprogesterone 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 4 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Desogestrel 150 microgram and ethinylestradiol 20 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely desogestrel 150 microgram and ethinylestradiol 30 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 30 microgram and levonorgestrel 150 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely ethinylestradiol 30 microgram and levonorgestrel 250 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 50 microgram and levonorgestrel 250 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 35 microgram and norethisterone 500 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol+norethisterone 35micrograms/1mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 20 microgram and norethisterone acetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely ethinylestradiol 30 microgram and norethisterone acetate 1.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely ethinylestradiol 30 microgram and gestodene 75 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol+gestodene+placebo 30micrograms/75micrograms tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 20 microgram and gestodene 75 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely ethinylestradiol 35 microgram and norgestimate 250 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 20mcg+progestogen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 30mcg+progestogen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 35mcg+progestogen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 50mcg+progestogen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol + levonorgestrel 0.15mg/0.03mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estrasorb	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol topical emulsion	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol topical emulsion 0.05mg/day	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estrasorb topical emulsion 0.05mg/day	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Levonorgestrel 0.015mg/day + estradiol 0.045mg/day transdermal system	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Climara pro	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Levonorgestrel + estradiol transdermal system	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Climara pro levonorgestrel 0.015mg/day + estradiol 0.045mg/day transdermal system	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely estradiol 2.083 microgram/1 hour prolonged-release vaginal ring (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol 600micrograms / norelgestromin 6mg transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinylestradiol and norelgestromin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing desogestrel 0.15 mg and ethinyl estradiol 0.01 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing only desogestrel 0.15 mg and ethinyl estradiol 0.03 mg/1 each oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 35 microgram and etynodiol diacetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 50 microgram and etynodiol diacetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol + etonogestrel 2.7mg/11.7mg vaginal ring	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 30 microgram and ferrous fumarate 75 mg and norgestrel 300 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Norelgestromin+ethinyl estradiol 6mg/0.75mg patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 1.25g/dose gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol + norethisterone acetate 1mg/0.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely desogestrel 100 microgram and ethinylestradiol 25 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 0.75mg/dose gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 5 microgram and norethisterone acetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 4.167 microgram/hour prolonged-release vaginal ring	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 20 microgram and ferrous fumarate 75 mg and norethisterone 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing precisely ethinylestradiol 30 microgram and ferrous fumarate 75 milligram and norethisterone 1.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 35 microgram and norgestimate 180 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinylestradiol and norgestimate (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinylestradiol and norethisterone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing desogestrel and ethinylestradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinyl estradiol and ethynodiol diacetate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinylestradiol and levonorgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Norethindrone + ethinyl estradiol + ferrous fumarate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol + norgestimate 0.035mg/0.25mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol acetate (substance)	Is a	False	Estradiol	Inferred relationship	Some
Estradiol 14mcg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing estradiol and norethisterone acetate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 0.05mg/norethindrone acetate 0.14mg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 0.05mg/norethindrone acetate 0.25mg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Aranelle	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinylestradiol and norgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Lutera 28 tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol 600micrograms / norelgestromin 6mg transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing sodium estrone sulfate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol 2.5 microgram and norethisterone acetate 500 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing drospirenone and ethinylestradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Drospirenone 2 mg and estradiol 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinyl estradiol 0.02mg / norelgestromin 0.15mg per day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Cyproterone acetate 2 mg and ethinylestradiol 35 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing cyproterone acetate and ethinyl estradiol	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing drospirenone and estradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	1
Drospirenone 500 microgram and estradiol 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing ethinylestradiol and gestodene (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Ethinylestradiol	Is a	False	Estradiol	Inferred relationship	Some
Product containing precisely estradiol 1 milligram and norethisterone acetate 500 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing estradiol and norethisterone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	2
Product containing estradiol and levonorgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	2
Product containing estradiol and norgestrel (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	2
Product containing estradiol and medroxyprogesterone acetate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 500 microgram and norethisterone acetate 100 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 0.25mg/dose topical gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Product containing dydrogesterone and estradiol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	2
Estradiol 1.53mg transdermal spray	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 0.06mg/day transdermal patch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol 2 mg and norethisterone acetate 1 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estradiol	Inferred relationship	Some
Estradiol-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	1
Product containing estradiol in nasal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	1
Product containing estradiol in vaginal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estradiol	Inferred relationship	Some	1
Topical estradiol allergy	Causative agent (attribute)	False	Estradiol	Inferred relationship	Some	1

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Id	Description	Lang	Type	Status	Case?	Module
24201011	Estradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
730100013	Estradiol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3721927018	17-beta estradiol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3722984013	E2 - estradiol	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core